Michael Ristow, MD

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Director, Inst. for Exp. Endocrinology @ Charité @ Humboldt University #Berlin;
Interested in #aging, #ageing, #Celegans, #diabetes, #endocrinology, #hormones, #longevity, #metabolism, #mitochondria, #mitohormesis, #redox, #ROS, #redox, and more; views are my own
Pleased to share a just published paper coming from a nice collaboration with Erick M. Carreira at ETH Zurich, and two (meanwhile former) Ph.D. students of ours, Carolin Thomas and Reto Erni. #aging #ageing #Celegans #mice #phytochemicals #carott #carotts
OpenAccess PDF via https://rdcu.be/dtbny
Pleased to announce openings for two fully funded PhD student positions in Healthy #Aging #Research (#biochemistry, #epidemiology, #bioinformatics, and related topics) at #Charite Berlin and #Humboldt University. Please apply by Sept 30th the latest. Please feel free to share & retweet, thank you. More details can be found here: https://karriere.charite.de/stellenangebote/detail/phd-student-positions-in-healthy-aging-research-biochemistry-bioinformatics-dfm
PhD student positions in Healthy Aging Research (Biochemistry & Bioinformatics) (d/f/m)

Part-time | 30.09.2023 | Campus Charité Mitte (CCM) /

Ernährung und Nahrungsergänzungsmittel

Deutschlandfunk
Bin heute im #Deutschlandfunk als Studiogast in der Sendung #Sprechstunde zum Thema '#Ernaehrung und #Nahrungsergaenzungsmittel - Versprechen auf ein langes gesundes Leben?' ab 10:08 Uhr zu hören; Link zur Audiodatei im Anschluss hier. #Gesundheit #Praevention #Supplemente @DLF
Verapamil extends beta-cell function in individuals with newly diagnosed type 1 #diabetes in a randomized controlled trial. #RCT https://jamanetwork.com/journals/jama/fullarticle/2801974/
Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes

This randomized clinical trial compares the effect of verapamil on pancreatic beta cell function vs placebo in children and adolescents with newly diagnosed type 1 diabetes.

#Sex differences in #healthspan and #lifespan responses to geroprotective #diet-ary interventions in preclinical models. #geroprotection #aging #ageing https://www.sciencedirect.com/science/article/abs/pii/S2468867323000214
JCI - SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes

The artificial #sweetener #erythritol increases risk for major adverse cardiovascular events, and is linked to heightened platelet reactivity and #thrombosis potential in humans. #CVD #stroke #myocardialinfarction #death #nutrition https://www.nature.com/articles/s41591-023-02223-9
The artificial sweetener erythritol and cardiovascular event risk - Nature Medicine

Metabolomics analyses reported an increased risk of cardiovascular disease associated with the artificial sweetener erythritol, supported by mechanistic studies showing that high levels of erythritol enhanced platelet reactivity and thrombosis formation.

Nature
Apple reportedly hits major milestone on blood glucose monitor

Apple kept the project under wraps for years, housing it in an unaffiliated startup called Avolonte Health, Bloomberg said.

Insider
Flavin-containing monooxygenases rewire #metabolism to promote #longevity through #tryptophan and one carbon metabolism in #Celegans. https://www.nature.com/articles/s41467-023-36181-0
FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans - Nature Communications

Flavin containing monooxygenase 2 (FMO-2) is known to increase lifespan under dietary restriction through incompletely understood mechanisms. Here the authors report that FMO-2 modifies tryptophan and methionine metabolic pathways to enhance stress resistance and slow aging in C. elegans.

Nature