Hacker News21h ago

Sugar industry influenced researchers and blamed fat for CVD

https://www.ucsf.edu/news/2016/09/404081/sugar-papers-reveal-industry-role-shifting-national-heart-disease-focus

#HackerNews #SugarIndustry #CVD #FatBlame #ResearchInfluence #HealthDebate #FoodPolitics

Sugar Papers Reveal Industry Role in Shifting National Heart Disease Focus to Saturated Fat

A newly discovered cache of industry documents revealed that the sugar industry began working closely with nutrition scientists in the mid-1960s to single out fat and cholesterol as the dietary causes of coronary heart disease and to downplay evidence that sucrose consumption was also a risk factor.

Sugar Papers Reveal Industry Role in Shifting National Heart Disease Focus to Saturated Fat | UC San Francisco
Carbon Petals4d ago

Carbon Petals Lab-Grown Diamond Jewelry

https://carbonpetals.com/

#labgrowndiamonds #diamonds #diamond #jewelry #labgrowndiamond #diamondring #engagementring #labgrowndiamondjewelry #labgrown #cvd #jewellery #finejewelry #cvddiamond #labdiamonds

enclatureDec 15
@Junes@clubcyberia.co @Forestofenchantment@clubcyberia.co Replication/recreation techniques keep improving #HPHT vs #CVD the lab grown diamonds are evidently getting reall really good.
Alexander J. SteinDec 5
The EAT-Lancet diet, which focuses on #plantbased foods, is linked to lower risk of cardiovascular disease in healthy people. In patients with cardiovascular #disease, it is linked to lower risk of non-fatal stroke & myocardial infarction: doi.org/10.1007/s003... #CVD #health #nutrition #diets

The relationship between the E...
The relationship between the EAT-Lancet dietary pattern and risk of cardiovascular events in patients with established cardiovascular disease - European Journal of Nutrition

Purpose To reduce the risk of recurrent cardiovascular events in patients with established cardiovascular disease (CVD), guidelines recommend adopting a more plant-based diet. The EAT-Lancet diet, which focuses on plant-based foods, is associated with a lower risk of CVD in apparently healthy people. However, the relationship in patients with established CVD is unclear. Therefore, the aim of this research was to quantify the relationship between the EAT-Lancet Healthy Reference Diet (HRD) and risk of recurrent CVD in patients with established CVD. Methods Patients with established CVD from the Utrecht Cardiovascular Cohort-Second Manifestations of ARTerial disease were studied. Dietary intake was measured using a food frequency questionnaire and the relationship between the EAT-Lancet HRD (score from 0 to 140 points) and non-fatal myocardial infarction and stroke was assessed using Cox regression adjusted for age, sex, educational background, lifestyle factors, and energy intake. Results During a follow-up of 24,212 person-years 209 non-fatal vascular events occurred. The median score for the EAT-Lancet HRD was 57 out of 140 points (IQR: 41–68). After adjustment for confounders, a diet more in line with the EAT-Lancet HRD was associated with a lower risk of non-fatal vascular events (HR 0.87 (95% CI 0.79–0.96) per 10-point increase); stroke (HR 0.76 (95% CI 0.63–0.91) per 10-point increase); and a trend towards lower risk of myocardial infarction (HR 0.90 (95% CI 0.81–1.02) per 10-point increase). Conclusion In patients with established CVD, a dietary pattern more in line with the EAT-Lancet HRD is associated with a lower risk of non-fatal stroke and myocardial infarction.

SpringerLink
Matt "msw" WilsonDec 4

Unpopular opinion: a vulnerability that was disclosed privately by researchers and had a coordinated response from vendors and service operators under an (albeit short) embargo is not a “0-day”.

#InfoSec #CVD

RDNNov 27

A twin study of over 3,000 people followed for approximately 11 years confirms that higher dietary polyphenol intake is associated with lower cardiovascular disease risk.

https://link.springer.com/article/10.1186/s12916-025-04481-5

#Science #Health #CVD #Diet #Polyphenols

Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort - BMC Medicine

Background Previous studies have reported inverse associations between total (poly)phenol intake or specific subclasses of (poly)phenols, estimated from dietary questionnaires, and cardiovascular disease (CVD) risk. However, no studies have examined (poly)phenol-rich dietary patterns and their corresponding urinary metabolite profiles in relation to CVD risk. This study investigated the associations between a (poly)phenol-rich dietary score (PPS-D), its urinary metabolic signature (PPS-M), and longitudinal CVD risk in the TwinsUK cohort. Methods We included 3110 participants (followed up for 11.20 ± 7.03 years) from TwinsUK who completed the EPIC-Norfolk Food Frequency Questionnaire with longitudinal data. A subset of 200 participants provided spot urine samples, in which 114 (poly)phenol metabolites were quantified using ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) to objectively measure (poly)phenol exposure. Associations between the PPS-D or PPS-M and CVD risk scores (ASCVD risk score and HeartScore), and biomarkers of CVD risk (blood pressure and lipid profile) were assessed using linear mixed models, adjusting for covariates and multiple testing (FDR < 0.05). Results PPS-D was negatively associated with ASCVD risk score (stdBeta: − 0.05 (− 0.07, − 0.04)) and Heartscore (stdBeta: − 0.03 (− 0.04, − 0.01)) (FDR-adjusted p < 0.01) in the overall population (n = 3,110). In the subgroup with urinary metabolites (n = 200), such significant associations were partially replicated through metabolites of flavonoids, phenolic acids, and tyrosols that significantly negatively associated with the ASCVD risk score, HeartScore, diastolic blood pressure (DBP), and positively with high-density lipoprotein cholesterol (HDL-C). In addition, a higher PPS-M was correlated with elevated HDL-C and lower blood pressure, ASCVD risk score, and HeartScore. Conclusions Higher adherence to a (poly)phenol-rich diet is associated with lower CVD risk, with consistent associations observed through urinary metabolite profiles, highlighting the long-term cardiovascular benefits of (poly)phenol consumption, particularly flavonoids and phenolic acids.

SpringerLink
RDNNov 7

Genomic sequencing of gut bacteria in people with and without coronary artery disease (14 & 28, respectively) identified 15 species of bacteria (out of 520) that are connected with the disease. Of these, 7 had higher abundance and 8 had lower abundance. Ten metabolic pathways were found to differ between the two groups, and bacterial influence on several of these pathways estimated.

Summary: https://asm.org/press-releases/2025/november/new-study-links-gut-microbes-to-common-heart-disea

Original paper: https://journals.asm.org/doi/10.1128/msystems.00954-25

#Science #Health #CVD #GutMicrobiome

New Study Links Gut Microbes to Common Heart Disease

A new study found that gut microbes likely play a role in coronary artery disease (CAD).

ASM.org
RDNNov 7

A double-blind clinical trial of the effect of metformin on exercise response, in 72 adults at risk for diabetes and heart disease, confirmed that metformin counters the beneficial effects of exercise, possibly though its action of blocking mitochondrial activity.

Summary: https://scienceblog.com/when-exercise-stops-working-how-metformin-blocks-the-bodys-gains/

Original paper (not open access): https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgaf551/8276136?redirectedFrom=fulltext

#Science #Health #Diabetes #CVD #Exercise #Metformin

When Exercise Stops Working: How Metformin Blocks the Body’s Gains

Exercise is supposed to help prevent diabetes, not lose its punch because of a drug meant to do the same thing. Yet new research from Rutgers University

ScienceBlog.com
Christian Lawson-PerfectNov 6

I have quite a strong colour vision deficiency. One way it affects me is that I often miss red text on a dark or green background.
I used to have an app on my phone that would shift colours from the camera, so that I could at least see where the colour changes, if not give it a name. At some point that app stopped working with new versions of Android

This morning, while the kids were playing Minecraft, I spent a few minutes making a little web page that shows your webcam feed, and applies a hue-rotate filter to it. Nice and simple!

In case anyone's interested in my process, here's a recording of my "see colours any%" speedrun:

https://media.aperiodical.com/colour-shuffle

The page itself is at https://colour-shuffle.think.somethingorotherwhatever.com/index.html

(if you don't have a camera it'll just look like an empty page)

#CVD #colourblind

Beach Spectre MEGA grant - update 1, 2025-10-14

clp
Dr. John Barentine FRASNov 5

Another health study backed by direct measurements of light exposure (rather than guessing what it is from satellite measurements): “In this cohort study, night light exposure was a significant risk factor for developing cardiovascular diseases among adults older than 40 years. These findings suggest that, in addition to current preventive measures, avoiding light at night may be a useful strategy for reducing risks of cardiovascular diseases.”

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2840489

#ALAN #LightPollution #HumanHealth #CVD #CardiovascularDisease