#Archaea & #microbiology folks - I'm curious. How do you feel about the dorado polish bacteria mode for your archaeal ONT long read assembled genomes? I know it holds up well with bacteria, but archaea's always been a bit funny.

Polypolish-pypolca combo is great, but they need short reads and I want to stick with long reads whenever I can (purely for logistic reasons)

#bioinformatics

Interested in the genetic secrets of your favorite plant?

A genome sequence might reveal them. We wrote down a workflow from DNA extraction & sequencing to genome sequence assembly & annotation. It includes a hands-on guide with example commands.

https://doi.org/10.1186/s12864-026-12623-z

#Genomics #Bioinformatics
@samnm
@boas_pucker

We just dropped a new release of SKiM -- ONT tailored metagenomic classifier that is currently the most efficient classifier in terms of memory and storage usage while remaining fast and extremely accurate. The new release comes with a new database format for improved speed and version control and a new caching mode that can be used to run in extremely low-memory settings. Check it out, spread the word, start using it :-)

https://gitlab.com/SCoRe-Group/SKiM

#bioinformatics #metagenomics #opensource

SCoRe-Group / SKiM · GitLab

Short K-mers in Metagenomics

GitLab

Pipeline release! nf-core/proteinfold v2.0.0 - Montseny Brook Newt!
Protein 3D structure prediction pipeline
Please see the changelog: https://github.com/nf-core/proteinfold/releases/tag/2.0.0

#alphafold2 #colabfold #esmfold #proteinfoldprediction #proteinfolding #proteinsequences #proteinstructure #nfcore #openscience #nextflow #bioinformatics

Release Montseny Brook Newt · nf-core/proteinfold

[2.0.0] - 2026-03-27 Enhancements & fixes [#177] - Fix typo in some instances of model preset alphafold2_ptm. [PR #178] - Enable running multiple modes in parallel. [#179] - Produce an interactive...

GitHub

Have you ever wanted to use recount3 processed data into #Python without using #RStats first to pull down the data?

Now you can! v 1.0 of the Python recount3 package is available! Docs are on GH, and you can install the package from pypi.

https://moseleybioinformaticslab.github.io/recount3/

#Bioinformatics #RNASequencing

/1

recount3 — recount3 1.0.0 documentation

#nfcore and #VirJenDB plan a hybrid #hackathon on 17 May as a satellite event of #ViBioM2026 toward #opensource #virus #bioinformatics workflows.

Proposed projects
- expand VirJenDB visualizations with an atlas
- work on an existing nf-core virus workflow
- port your tool to bioconda and other #Nextflow prep

👉 Propose your project and indicate your interest: https://forms.gle/KWJYPCXgGotmrhCu8.

📝 Registration opens April 2026! More: https://tinyurl.com/mefewbw4.

#EVBC #deNBI

Huh, if you're running Canu (yes, it's deprecated), latest conda installation of Canu doesn't play nice with java on linux. Solution is to just change the line 1078 at the lib/perl5/site_perl/canu/Defaults.pm to point toward working java installation, like:

$java="/your/java/bin";

#bioinformatics

Bioinformatics Open Days 2026 is starting!

#bioinformatics #conference