FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans - Nature Communications

Flavin containing monooxygenase 2 (FMO-2) is known to increase lifespan under dietary restriction through incompletely understood mechanisms. Here the authors report that FMO-2 modifies tryptophan and methionine metabolic pathways to enhance stress resistance and slow aging in C. elegans.