I wondered if MrgprD has anything to do with IBS, and apparently it does - particularly with IBS-C, which is what I have.
5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein–coupled receptor D [2018]
https://eprints.gla.ac.uk/176184/
NOCICEPTION - AS THE STONE MEETS FLESH [OFFICIAL VISUALIZER] (2026) SW EXCLUSIVE
NOCICEPTION "AS THE STONE MEETS FLESH" OUT NOW!
"I can't see anything!"
- "Sir. You're trying to use the nociceptors for vision. They literally can't."
Unlocking the Secrets of the Mind and Body: A Journey into Interoception and Emotion
#MindBodyConnection #Interoception #BloodBrainBarrier #Emotions #Nociception #Antinociception #SelfAwareness #MentalHealth #Neuroscience #ExploreYourMind #BrainScience #Mindfulness #EmotionalIntelligence #ScienceExplained #GeomagneticField
Study offers a potential pathway for safer, non-addictive pain management
"The study showed that when D₂O passed through the TRPV1 channel, it suppressed pain signal transmission and achieved effective analgesia."
They studied both human cells in vitro and mice. This is good since another study found that D2O activated sweet taste receptors in humans, but not in mice -
Sweet taste of heavy water
https://www.nature.com/articles/s42003-021-01964-y
#HeavyWater #D2O #solvents #TRPchannels #SweetTasteReceptors #Pain
#nociception #TRPV1 #neuroscience #biology #MouseVsHuman
Researchers from the National University of Singapore (NUS), in collaboration with Peking University, China, have made a discovery regarding the TRPV1 (transient receptor potential vanilloid 1) ion channel and its role in pain perception.
PhD Position in Neural Mechanisms of Nociceptive Perception and Modulation, in the lab of Carlotta Martelli, Johannes Gutenberg University Mainz, Germany.
To apply, write to Martelli directly, see below:
Understanding the roots of chronic pain
"A team of researchers led by Oscar Sánchez-Carranza in Professor Gary Lewin's lab at the Max Delbrück Center have identified a new function for the PIEZO2 protein -- in mediating chronic pain hypersensitivity. The research suggests a new target for analgesics and potentially explains why pain medications that target voltage gated sodium channels have been disappointing as clinical targets. "
https://www.sciencedaily.com/releases/2024/07/240711111439.htm
#ChronicPain #Piezo #Piezo2 #nociception #neuroscience #fibromyalgia
Dr. Jarred Younger, PhD will be doing a weekly YouTube series on the latest research on pain and chronic illnesses such as fibromyalgia, ME/CFS, Long Covid and Gulf War Syndrome.
🙂 ❤️
https://youtu.be/ZWWM6duVScE?si=VSatnYUYwMlxlUQX
#fibromyalgia #ChronicPain #MECFS #LongCovid #GulfWarSyndrome
#GulfWarIllness #MCAS
#AutoimmuneDiseases
#neuroinflammation #nociception #Pain #inflammation
El Pregoner del Metall
Rhyothemis
Gravitas
Coffee (Team CW)
CITO Greenhouse
Albert Cardona