Tom KindlonNews Release 11-Sep-2025:
"New diagnostic code for Gulf War illness marks major step forward for veteran care and research: Official recognition will support better diagnosis, treatment and understanding of Gulf War illness"
Dysregulation of lipid metabolism, energy production, and oxidative stress in myalgic encephalomyelitis/chronic fatigue syndrome, Gulf War Syndrome and fibromyalgia
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1498981/full
From the latest Science for ME weekly update
@mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @fibromyalgia
#Fibromyalgia #Fibro #FMS #FM #GulfWarSyndrome #GulfWarIllness #GWI
From the MassME newsletter
Study of interplay of cellular landscapes and the role of oxidative stress in various conditions
https://www.umassmed.edu/slusslab/reclaim-study/
#MEcfs #hEDS #HypermobilitySyndrome #Orthostaticintolerance #POTS #LongCOVID @fibromyalgia
#Fibromyalgia #Fibro #FMS #FM #ChronicLyme
#GulfWarIllness @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome @longcovid
RhyothemisNew findings: more evidence of poor oxygen perfusion in the brain
https://youtu.be/g4hLI5ktOhE?si=6vbxMnDAGKCfUNsd
"We seeing high levels of lactate and low levels of choline in the brains of Gulf War Illness sufferers. This quick update covers our new analyses and why the may be important to those with chronic pain, fatigue, and cognitive issues. - Jarred Younger"
#GulfWarIllness #ChronicIllness #ChronicPain #choline #lactate
#BrainPerfusion
#MECFS
New lab results - low brain oxygen in chronic disease
https://youtu.be/kwj2UyE0xlo?si=xuhv0aVMXSHo9cBj
new results from Dr Younger's Neuroinflammation, Pain and Fatigue Lab
Jarred Younger: Research priorities for the second half of 2024
In this short video (9 minutes) Dr. Younger lists the major projects he is running in the second half of 2024.
https://www.youtube.com/watch?v=vePEtCKjkfA
#MEcfs #CFS #PwME #GulfWarIllness #GWI #Fibromyalgia #Fibro #FMS #FM @fibromyalgia @mecfs
020 - Research priorities for the second half of 2024
The brain's inflammation thermostat -
Dr Jarred Younger discusses a new research study that identified a key brain region for upregulating and downregulating inflammation.
https://youtu.be/71V4cbcUuok?si=3_1zu21Tf7W7Mbn_
#Immunology #Inflammation #Neuroscience #VagusNerve #MECFS #GulfWarIllness #fibromyalgia
021 - The brain's inflammation thermostat
INIM May 2024 Conference Videos are now available.
Find this post here:
https://us4.forward-to-friend.com/forward/preview?u=419072c88a85f355f15ab1257&id=ab6ab16c7e
Alternatively INIM YouTube channel is here:
https://www.youtube.com/@NSU_INIM/videos
#MEcfs #CFS #PwME #GulfWarIllness #GWI #LongCovid #chronicillness @mecfs @longcovid
New 12-minute video:
"I believe microglia are the primary culprit behind #fibromyalgia, #MECFS, #GulfWarIllness, #LongCOVID, and other #chronicpain & fatigue disorders.
Here is a quick video on what I am trying to do to fix the problem. - Jarred Younger"
https://www.youtube.com/watch?v=XggO__DlALw
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #CFS #PwME @longcovid
#PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC
@chronicpain @fibromyalgia
#Fibro #FMS #FM
014 - When glia are the bad guys
Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders
https://www.mdpi.com/2073-4409/13/6/511
This paper has section which discusses ME/CFS & #gulfwarillness as a chronic disorder that is associated with neuroimmune dysfunctions
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #gwi #gulfwarsyndrome
Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders
Neuroinflammatory and neurodegenerative disorders including Alzheimer’s disease (AD), Parkinson’s disease (PD), traumatic brain injury (TBI) and Amyotrophic lateral sclerosis (ALS) are chronic major health disorders. The exact mechanism of the neuroimmune dysfunctions of these disease pathogeneses is currently not clearly understood. These disorders show dysregulated neuroimmune and inflammatory responses, including activation of neurons, glial cells, and neurovascular unit damage associated with excessive release of proinflammatory cytokines, chemokines, neurotoxic mediators, and infiltration of peripheral immune cells into the brain, as well as entry of inflammatory mediators through damaged neurovascular endothelial cells, blood–brain barrier and tight junction proteins. Activation of glial cells and immune cells leads to the release of many inflammatory and neurotoxic molecules that cause neuroinflammation and neurodegeneration. Gulf War Illness (GWI) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are chronic disorders that are also associated with neuroimmune dysfunctions. Currently, there are no effective disease-modifying therapeutic options available for these diseases. Human induced pluripotent stem cell (iPSC)-derived neurons, astrocytes, microglia, endothelial cells and pericytes are currently used for many disease models for drug discovery. This review highlights certain recent trends in neuroinflammatory responses and iPSC-derived brain cell applications in neuroinflammatory disorders.