Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mick &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field
@PLOSBiology plos.io/48u6mle
What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @PLOSBiology https://plos.io/4mI4lVO

Something I always wondered about people with #tourettes and #ticdisorders:

We're almost always empaths.

The part of our brain - the #prefrontalcortex - responsible for #empathy is slightly larger than usual while the part of our brain in our #basalganglia regulating motor planning/control, has faulty neuro-pathways and shrunken parts.

More connections to the PFC as an adaptation, resulting in glitchy motor controls but perhaps very deep emotions.

#writing #mentalhealth #neuroscience

Lateral #PrefrontalCortex is involved in executive functions, but what roles do distinct anatomical subregions play? This study shows that caudal VLPF specializes in visual input processing, while middle areas support context-based behavioral planning @PLOSBiology https://plos.io/4ljEz9W
What role do cortical regions play in #mathematical learning? This study reveals the causal role of dorsolateral #PrefrontalCortex & #frontoparietal network in #math learning using #transcranial neuromodulation in human participants @PLOSBiology https://plos.io/45SyMUI

#mircostressors can be an insidious trap!

Experts Are Sharing Why You Get So "#Mean" When You're Overwhelmed, And Thankfully There's Such A Simple Solution https://www.yahoo.com/lifestyle/articles/exactly-why-mean-youre-overstimulated-152627504.html

#overstimulation #prefrontalcortex #technology #deepbreathing #mindfulness #calm

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The medial #PrefrontalCortex (mPFC) is a key brain area for pain sensation & #ChronicPain. This study shows that modulation of a circuit projecting from nucleus reuniens of the thalamus to mPFC improves neural & behavioral indicators of chronic pain in mice @PLOSBiology https://plos.io/4mpMuEj
Excitatory projections from the nucleus reuniens to the medial prefrontal cortex modulate pain and depression-like behaviors in mice

The medial prefrontal cortex (mPFC) is a key brain area for pain sensation and chronic pain. This study shows that modulation of a circuit projecting from the nucleus reuniens of the thalamus to the mPFC improves neural and behavioral indicators of chronic pain in mice.