🗺️🐀 How does the #brain map uneven terrain? New paper by @rmgrieves, @elduvelle_neuro & Taube suggests that the #hippocampal map is shaped by terrain #geometry itself, not only by where the animal runs. Slopes, ridges & surface contours may act as spatial structure for #PlaceCells. Read more about in the 🧵👇

📄 https://doi.org/10.1126/sciadv.adz9893
"Hippocampal #PlaceCells map terrain geometry independently of #behavior"

#Hippocampus #SpatialNavigation #Neuroscience https://fediscience.org/@rmgrieves/116692850991318267

RE: https://fediscience.org/@rmgrieves/116692850991318267

“This is a hill I’ll die on!” - says the scientist feeding smelly paste to rats running in a home-made maze with hills and troughs just like the waves in the rat’s brain and the emotions in the scientist’s life… 🏔️ 🌊 🧠

@rmgrieves 's latest paper is out, with rats on hills, #PlaceCells recordings and modelling looking at how the brain maps real-life environments: Hippocampal place cells map terrain geometry independently of behavior

It was great fun to work with him and Jeff Taube on this, even with all the emotional rollercoasters (inherent to science-making)!

#Neuroscience #Hippocampus #3DMapping #NeuroRat #SpatialCognition

💁🏻‍♀️ TIL: Using ultra-thin Neuropixels probes, #Baylor College researchers found the #hippocampus processes #speech and predicts upcoming #words during #anesthesia. 🧠

Over 70% of #neurons distinguished unexpected #sounds from predictable ones. This challenges the idea that understanding #language requires consciousness. 😪

👉 https://www.sciencenews.org/article/brain-cells-listen-under-anesthesia

#neuroscience #brain #hearing #science #houston #nature #learning

New paper by Maimon et al (Ulanovsky lab): recordings from #bats flying through tunnels up to 200 m reveal a sparse-to-dense transformation between #hippocampal #CA3 and #CA1.

In small environments, CA3 and CA1 #PlaceCells look similar. At large spatial scales, however, CA3 #neurons mostly show single, ultrasparse #PlaceFields, while CA1 neurons show dense multifield coding.

🌍 https://doi.org/10.1038/s41586-026-10537-0

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#Neuroscience #Hippocampus #SpatialNavigation #NeuralDynamics

Stress disrupts hippocampal integration of overlapping events, memory inference

https://www.science.org/doi/10.1126/sciadv.aea5496?user_id=66c4bf745d78644b3aa57b08

#HackerNews #stress #memory #neuroscience #hippocampus #research #science