What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @PLOSBiology https://plos.io/4mI4lVO
Before you continue to YouTube

Chronic #trypanosome brain infection induces meningeal responses resulting in ectopic lymphoid aggregates containing #autoreactiveBcells; #autoantigens include MBP, consistent with experimentally observed #demyelination @Jquintanalcala &co #PLOSBiology https://plos.io/3R8xgpH
The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection

This study shows that chronic brain infection with African trypanosomes induces broad meningeal responses resulting in the development of ectopic lymphoid aggregates containing autoreactive B cells; myelin basic protein is one of the autoantigens detected by autoreactive B cells, consistent with the cortical demyelination observed in experimental infections.

@[email protected] Thank you for mentioning this great study!

My vision deteriorated for several months after my 2nd Covid infection, and my eyes hurt when watching from left to right. After reading this article and looking certain things up, I think it must have been neuritis optica!

Mind you, after my first infection I got all sorts of B12-deficiency symptoms, which made me suspect that there was a demyelinating process going on.

1/n

#COVID19
#demyelination
#B12deficiency

Injecting fractalkine into mouse models of multiple sclerosis increased the number of oligodendrocytes. Findings suggest fractalkine may help to slow the progression, or potentially halt Multiple Sclerosis.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neuroimmunology #Neuroinflammation #Demyelination #DemyelinatingDiseases #MultipleSclerosis #Oligodendrocytes #Fractalkine

https://neurosciencenews.com/multiple-sclerosis-fractslkine-222344/

How a Brain Molecule Could Halt Multiple Sclerosis - Neuroscience News

Neuroscience News provides research news for neuroscience, neurology, psychology, AI, brain science, mental health, robotics and cognitive sciences.

Neuroscience News

New research shows that the drug Riluzole, approved by the U.S. Food and Drug Administration to treat certain forms of amyotrophic lateral sclerosis, can at least partially correct the molecular cause of some leukodystrophies.

#Neuroscience #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #RareDiseases #Leukodystrophies #Demyelination #DemyelinatingDiseases #Riluzole

https://neurosciencenews.com/myelin-neuropharmacology-21997/

New Drug a Hopeful Advance for Incurable Neurodegenerative Myelin Diseases - Neuroscience News

Neuroscience News provides research news for neuroscience, neurology, psychology, AI, brain science, mental health, robotics and cognitive sciences.

Neuroscience News