You’re not unmotivated. Your reward system is depleted.

Anhedonia — the inability to feel pleasure — is one of the core features of depression most people don’t talk about. Your dopamine system has gone quiet, so nothing feels worth the effort.

Treatment doesn’t just reduce sadness. It brings the reward system back online.

https://youtube.com/shorts/tOd6feh6SKg?si=StTAkFQYEvAtKJt3

#DrTraceyMarks #anhedonia #autism #ASD #depression #dopamine #ADHD #AuDHD #AutisticMenopause #MentalHealth #menopause

#Dysentery
#Anhedonia
#357Homicide
#Juggernaut

28/05/2026

#DeathMetalViolenceTour
#DeathMetalViolenceTour2026

#RockNEat

https://www.purgatoire.fr/concerts/c-669_2026-05-28_death-metal-violence-tour-2026

The article discusses a synthetic psychedelic compound, 25C-NBF, that promotes rapid brain cell growth and produces antidepressant-like effects in male rodents with no evident addictive traits. It also examines the compound’s safety profile, neuronal changes, and potential for fast-acting mood improvement.

This topic is of interest to psychology enthusiasts because it highlights how rapid neuroplastic changes can influence mood regulation and behavior, offering insight into mechanisms of depression and the quest for fast-acting treatments.

Article Title: Novel psychedelic compound 25C-NBF shows rapid antidepressant effects without addictive traits

Link to PsyPost Article: https://nolinkpreview.com/www.psypost.org/novel-psychedelic-compound-shows-rapid-antidepressant-effects-without-addictive/

#psychedelics #depression #neuroplasticity #5HT2A #psychopharmacology #neuroscience #mentalhealth #anhedonia #dopamine #prefrontalcortex

ARP 410 If depression is the road dog to anxiety then anhedonia is the side chick to depression.

In this episode, a look a the pleasure blocker experience of anhedonia.
#MentalHealth #Treatment #Anxiety #Anhedonia

https://www.anxietyroadpodcast.com/2026/05/arp-410-what-is-anhedonia.html

But with GLP-1s, there can sometimes be too much of a good thing. The drugs can be so effective at blocking #foodnoise and reducing the release of dopamine that they can cause #anhedonia: a reduced ability to feel pleasure."

{Off the menu: GLP-1s can help patients lose weight. For some, they also erase the joy of food}

https://globe2go.pressreader.com/article/281492167921324

#glp1drugs
#glp1pill
#weightloss
#weightmanagement

In this Substack, I reveal the sleight of hand psychologists use to domesticate ideas from philosophy and other disciplines by critiquing an essay on nihilism and Anhedonia.

https://open.substack.com/pub/brywillis634737/p/nihilism-is-not-a-symptom?utm_campaign=post-expanded-share&utm_medium=web

#Nihilism #ExistentialNihilism #PsychologyCritique #Anhedonia #Metaethics #LanguageInsufficiency #Philosophy #MeaningOfLife #SemanticDrift #LanguageInsufficiency #PsychologyCritique #blog #podcast #essay #reading #writing #pathology

Right now. I'm firing on all cylinders.

But it's not always been this way.

During my brush with cancer, I experienced a state of anhedonia. This is when you no longer take pleasure in the things you used to find pleasurable.

If you are suffering from anhedonia, please know that this state can be temporary. It was temporary for me.

I don't know what pulled me out of it, or how I got myself out of it. Still, it was temporary.

#anhedonia

Ah....the "hope parade" is in "told you so" mode.

We're a long way from fascist-free. Enjoy the win. There's still work to do.

#Anhedonia #WelcomeToMyHead #ThisIsAsGoodAsItGets

This article examines how genetic risk for anhedonia is linked to distinct patterns of brain activity during reward processing, using polygenic risk scores and fMRI during a monetary incentive delay task. Findings suggest lower activation in reward-related regions during anticipation and feedback phases in those with higher genetic risk.

This piece is of interest to psychology readers because it connects genetic factors with neural mechanisms of motivation and pleasure, illustrating how biology can shape cognitive and affective processes involved in reward.

Article Title: Genetic risk for anhedonia linked to altered brain activity during reward processing

Link to PsyPost Article: ift dot tt/THsvVta

Copy and paste broken link above into your browser and replace "dot" with "." for link to work. We have to do it this way to avoid displaying copyrighted images.

#genetics #anhedonia #rewardprocessing #fMRI #psychobiology