Mastodawn

Summary: The article discusses how loneliness alters brain processing of social information and how targeted brain stimulation can shift lonely individuals' subjective evaluation of negative social scenes, revealing a disconnect between brain activity and conscious feelings. It reports on a study using transcranial direct current stimulation on the left dorsolateral prefrontal cortex and examines differences between lonely and non-lonely participants.

Why it matters for psychology: The piece highlights the complex relationship between neural processing and subjective experience in loneliness, illustrating how brain modulation can influence perceived negativity and challenge assumptions about self-awareness in emotion regulation. It also underscores the role of metacognition and lateralized prefrontal functioning in social threat processing.

Article Title: Study finds a disconnect between brain activity and feelings in lonely people

Link to PsyPost Article: ift dot tt/3M60n2k

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#loneliness #neuroscience #emotionregulation #prefrontalcortex #psychologyresearch

PLOS Biology Oct 23

Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mick &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field
@PLOSBiology plos.io/48u6mle

PLOS Biology Oct 1

What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @PLOSBiology https://plos.io/4mI4lVO

RationizedInsanity🏳️‍🌈🇺🇦🇨🇦🇬🇱🇵🇸Sep 30

Something I always wondered about people with #tourettes and #ticdisorders:

We're almost always empaths.

The part of our brain - the #prefrontalcortex - responsible for #empathy is slightly larger than usual while the part of our brain in our #basalganglia regulating motor planning/control, has faulty neuro-pathways and shrunken parts.

More connections to the PFC as an adaptation, resulting in glitchy motor controls but perhaps very deep emotions.

#writing #mentalhealth #neuroscience

PLOS Biology Aug 8, 2025

Lateral #PrefrontalCortex is involved in executive functions, but what roles do distinct anatomical subregions play? This study shows that caudal VLPF specializes in visual input processing, while middle areas support context-based behavioral planning @PLOSBiology https://plos.io/4ljEz9W

PLOS Biology Jul 3, 2025

What role do cortical regions play in #mathematical learning? This study reveals the causal role of dorsolateral #PrefrontalCortex & #frontoparietal network in #math learning using #transcranial neuromodulation in human participants @PLOSBiology https://plos.io/45SyMUI