U01.01.124 Glycogen Structure and Metabolism: Energy Storage

Master the biochemistry of glycogen (U01.01.124) for USMLE Step 1. Learn about $Latex \alpha(1,4)$ and $Latex \alpha(1,6)$ bonds, Glycogenin, and the differences between liver and muscle storage. High-yield guide on mymedschool.org.

mymedschool.org
U01.01.119 Alkaptonuria: Homogentisate Oxidase and Black Urine Disease

Master Alkaptonuria (U01.01.119) for USMLE Step 1. Learn the biochemistry of homogentisate oxidase deficiency, ochronosis, and the classic "black urine" presentation. High-yield guide on mymedschool.org.

mymedschool.org
U01.01.118 Maple Syrup Urine Disease (MSUD): Branched-Chain Amino Acids

Master Maple Syrup Urine Disease (MSUD) with our U01.01.118 guide. Learn about the deficiency of Branched-Chain Alpha-Keto Acid Dehydrogenase, the "sweet" scent of earwax, and high-yield management for USMLE Step 1. Available on mymedschool.org.

mymedschool.org
U01.01.117 Phenylketonuria (PKU): Screenings, Symptoms, and Management

Master Phenylketonuria (PKU) with our U01.01.117 guide. Understand the deficiency of Phenylalanine Hydroxylase (PAH) and BH4, the accumulation of phenylketones, and high-yield management strategies. Essential USMLE Step 1 biochemistry on mymedschool.org.

mymedschool.org
U01.01.111 Urea Cycle: Enzymes, Intermediates, and Hyperammonemia

Master the Urea Cycle with our U01.01.111 guide. Learn the rate-limiting enzyme CPS1, the mnemonic for intermediates, and the clinical impact of Ornithine Transcarbamylase (OTC) deficiency. High-yield USMLE biochemistry on mymedschool.org.

mymedschool.org
#MetabolicPathways fans: We've got you in FB2026_01! New reports include (links at https://flybase.org/static/new-this-release ):
L-VALINE CATABOLISM, L-ISOLEUCINE CATABOLISM, L-LEUCINE CATABOLISM, L-LYSINE CATABOLISM,
L-METHIONINE CYCLE, L-METHIONINE SALVAGE PATHWAY,
L-CYSTEINE BIOSYNTHESIS, L-PROLINE BIOSYNTHESIS
L-SERINE BIOSYNTHESIS, GLYCINE BIOSYNTHESIS,
GLYCINE CLEAVAGE SYSTEM,
L-PHENYLALANINE AND L-TYROSINE METABOLISM, L-ASPARTATE AND L-ASPARAGINE METABOLISM, L-GLUTAMATE AND L-GLUTAMINE METABOLISM,
FlyBase: New In This Release

FlyBase: a database for drosophila genetics and molecular biology

8-Jan-2026
Researchers search for why some people’s #gut #microbes produce high alcohol levels

Researchers have identified specific gut bacteria and #metabolicPathways that drive #alcohol production in patients with #autoBrewerySyndrome (ABS), a rare and often misunderstood condition in which people experience #intoxication without drinking alcohol

https://www.eurekalert.org/news-releases/1111885

#science #metabolism #ethanol #physiology

Researchers search for why some people’s gut microbes produce high alcohol levels

Mass General Brigham study of 22 people with a rare condition known as auto-brewery syndrome has found a link between gut microbes and intoxication symptoms, pointing to new treatment strategies

EurekAlert!

and a GO-Causal Activity Model (GO-CAM https://geneontology.org/docs/gocam-overview/) that is based directly on GO annotation data.

Useful links to external resources (FlyCyc, Reactome, KEGG) and publications are provided, as well as options to export the gene list to analysis, download and orthology tools.

For more information, see this Commentary: http://flybase.org/commentaries/2024_12/MetabolicPathways.html

#FlyBaseTootorial #GeneGroups #MetabolicPathways

GO-CAM overview

Introduction to GO-CAMs

Gene Ontology Resource
Autism could be diagnosed with stool sample, scientists say

Researchers found differences in the gut microbes of autistic people, raising hopes for faster diagnosis

The Guardian
Check out the Biochemical Pathways search at SGD (yeastgenome.org)!
SGD blog post here: https://www.yeastgenome.org/blog/biochemical-pathways-now-in-sgd-search
(grabbed from our buds at @yeastgenome on Twitter):
YeastPathways database of #metabolicPathways, #enzymes in #buddingYeast #Saccharomyces #cerevisiae is manually curated by SGD biocurators. Search category “Biochemical #Pathways” is now available with facets (subcategories) for References, Loci
https://yeastgenome.org/search?q=&category=pathway
Biochemical Pathways now in SGD Search | SGD

The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae.