FlyBase

@FlyBase@mstdn.science
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Curating and cataloging the world's data for the fruit fly Drosophila melanogaster into our database at http://flybase.org. Aiding discovery since 1992.

RE: https://genomic.social/@AllianceGenome/115883108547833326

ICYMI, this month's Alliance webinar, "MCP-What is it and what can it do for you?", presented by Lincoln Stein, is now on the Alliance YouTube channel.
https://www.youtube.com/watch?v=DELYj8BOpWk
Want to know about future or past webinars? Check the Alliance Event Calendar https://www.alliancegenome.org/event-calendar

The December #TechnicalAdvances are here! If you want your paper with a new technique , reagent, or resource featured in an upcoming update, make sure to flag it when you #FTYP!
https://wiki.flybase.org/wiki/FlyBase:Papers_with_technical_advances#Dec_2025
FlyBase:Papers with technical advances - FlyBase Wiki

This month's Alliance webinar "MCP-What is it and what can it do for you?", presented by Lincoln Stein, will be Thurs. Jan. 15 at noon ET. To get the Zoom link, please register https://tinyurl.com/4f9ycybt by Thurs. Jan 14 (before 11:00pm ET).
Join us to learn about model context protocols for AI agents.
Alliance Of Genome Resources Event Registration

Webinar recordings are posted at https://www.youtube.com/@AllianceOfGenomeResources A schedule of future events is on the Alliance Events Calendar https://www.alliancegenome.org/event-calendar

Google Docs
Alliance version 8.3.0 is now live at https://alliancegenome.org. Release notes are here https://www.alliancegenome.org/release-notes
Alliance of Genome Resources

Updated in FB2025_05: We've added 9 new binary drivers to the Frequently Used GAL4 and Other Binary System Drivers resource https://flybase.org/GAL4/freq_used_drivers/, which documents all binary drivers curated to at least 15 (lexA) or 20 (GAL4) papers.

You can find a link to the Frequently Used GAL4 and Other Binary System Drivers resource at the bottom of the GAL4 etc QuickSearch tab.

FlyCyc represents all the metabolic reactions and pathways of Drosophila melanogaster, computed by combining comprehensive pathway data at BioCyc (MetaCyc) with the set of manually curated/reviewed Gene Ontology annotations at FlyBase

Links from FlyBase gene reports to FlyCyc pathway pages have been updated to reflect the latest associations.

You can find those links in the Linkouts subsection of the External Crossrefereences and Linkouts section of Gene Reports.

We have recently updated FlyCyc https://biocyc.org/DMEL/organism-summary, the pathway-genome database representing Drosophila metabolism, to include enzymatic complexes as well as further improvements to enzyme annotations. #FlyCyc is now classed as a ‘Tier 1 Highly Curated Organism Database’.

We are grateful to AWS for their generous sponsorship of this data repository, which enables broader access to both current and archival FlyBase data for the Drosophila research community.

For more information, see the Downloads Overview (https://wiki.flybase.org/wiki/FlyBase:Downloads_Overview) or the Registry of Open Data on AWS (https://registry.opendata.aws/), and the FlyBase Commentary https://flybase.org/commentaries/2025_12/AWSOpenData.html

FlyBase:Downloads Overview - FlyBase Wiki

The FlyBase S3 bucket https://s3ftp.flybase.org/index.html now hosts over 4 terabytes of data, including all FlyBase releases from FB2006_01 through the current release, with access to bulk data files, genome sequences, precomputed reports, and historical datasets for reproducibility studies and comparative analyses across release versions.
Index of /

New with FB2025_05: Archive data is back!
FlyBase is now participating in the Amazon Web Services Open Data Sponsorship Program. AWS sponsors the storage & data transfer costs for the FlyBase bulk data repository, allowing us to preserve & provide access to nearly two decades of archive releases.