Happy to announce our latest publication in BMC Genomics! 🎉

🧬 CoExpPhylo – a novel pipeline for biosynthesis gene discovery

We combine co-expression with phylogenetic analysis to uncover biosynthetic pathways at scale.

📖 Read more: https://doi.org/10.1186/s12864-025-12061-3

#Bioinformatics #Genomics #Evolution #BigData #Pathways
@PuckerLab @samnm

@brianvastag i bet they are monoclonal Ab and basically protein peptides #pathways ?

Are they monoclonal antibody drugs or peptides?

The drugs mentioned—abrocitinib (Cibinqo), baricitinib (Olumiant), and upadacitinib (Rinvoq)—are small‑molecule JAK inhibitors, not monoclonal antibodies or peptides
Sick Times+1
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These are orally administered synthetic compounds, typically crafted by medicinal chemistry, that block kinase activity (JAK/STAT signaling) within immune cells. They're not protein-based biologics and thus not produced in bacteria.

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