FlyBaseSep 26

You can now search FlyBase and WormBase sequence data using the Alliance of Genome Resources BLAST server: www.alliancegenome.org/blastservice The Fly interface allows searching against many arthopods, or a search can be restricted to only Drosophila melanogaster databases.

#FlyBaseTootorial #AllianceGenomeTootorial #BLAST

FlyBaseApr 28, 2025
New in FB2025_02: All Gene Group class pages,, including #SignalingPathway, #MetabolicPathway, #MacromolecularComplex and #GeneGroup reports, now have #InteractiveTables enabled.
As with other interactive tables, users can customize the 'Members' table by reordering or filtering columns, or filtering which columns to display.
#FlyBaseTootorial
Show threadFlyBaseDec 23, 2024

and a GO-Causal Activity Model (GO-CAM https://geneontology.org/docs/gocam-overview/) that is based directly on GO annotation data.

Useful links to external resources (FlyCyc, Reactome, KEGG) and publications are provided, as well as options to export the gene list to analysis, download and orthology tools.

For more information, see this Commentary: http://flybase.org/commentaries/2024_12/MetabolicPathways.html

#FlyBaseTootorial #GeneGroups #MetabolicPathways

GO-CAM overview

Introduction to GO-CAMs

Gene Ontology Resource
FlyBaseSep 11, 2024

There's a surprise update to the #GAL4etc #QuickSearch tab!

As of today, the search results of this tab include #SplitSystemCombination hits.
#SplitGAL4 #hemidriver #FlyBaseTootorial

Show threadFlyBaseJun 28, 2024
As part of a collaboration with the EMBL-EBI Complex Portal https://www.ebi.ac.uk/complexportal/home many fly complexes have been added to this resource and 194 Macromolecular Complex Reports have corresponding entries.
#FlyBaseTootorial #MacromolecularComplexes #GeneGroups
Complex Portal

EMBL-EBI

Show threadFlyBaseJun 27, 2024
Please check out this Commentary about the #GeneToolKit https://flybase.org/commentaries/2024_06/GeneToolkit.html
#FlyBaseTootorial
FlyBaseApr 23, 2024
The combination pages have been added to hitlists, so if you search for a regulatory region that drives expression of one of the hemidrivers in a combination (e.g. R72B05, VT064569, ple) you'll see the relevant combination(s) in the hitlist.
These new report pages will get improvements during the coming months, including images of expression patterns when available.
#Split_GAL4
#hemidriver
#FlyBaseTootorial
Show threadFlyBaseFeb 26, 2024

You can also find the Transgenic Product class on Allele and Transgenic Construct reports.

#FlyBaseTootorial #GeneticToolkit

FlyBaseDec 15, 2023
This release brings an update to #OrthoDB in FlyBase; we've worked with the OrthoDB https://www.orthodb.org/ team to implement a new API call that improves the accuracy of OrthoDB-derived #orthologs shown in FlyBase.
We use OrthoDB for ortholog calls of Dmel genes in many organisms (other than those represented in the FlyBase implementation of DIOPT), including other Drosophila species & arthropods.
@ensembl #FlyBaseTootorial
OrthoDB | genes orthologs | Zdobnov lab

Show threadFlyBaseAug 8, 2023
Click on the SO term in the “Transgenic product class” field of an Allele Report get a list of all transgenes encoding a particular type of gene product.
On the Term Report (located in the #Vocabularies tool http://flybase.org/vocabularies), you can click on the Alleles button to get a hit list of all of all the matching transgenic alleles.
#FlyBaseTootorial #TransgenicProductClass #SequenceOntology