Mastodawn

The constant complaining that I have an alcohol problem each time I even look at a glass of wine is driving me to drink.

#life #leisure #alcohol

The Optimist Daily: Making Solutions the News [Unofficial]21h ago

Zebra striping can cut hangovers, with one important catch

https://fed.brid.gy/r/https://www.optimistdaily.com/2026/06/zebra-striping-can-cut-hangovers-with-one-important-catch/

caskfan 5h ago

@caskfan was drinking a #15 by #Flacks at #TheGreenManAleAndCiderHouse on Wednesday at 16:21 Served from cask, I rated it at 3.75 (good to great) #beer #alcohol #untappd #beersofmastodon

Noah Peterson 6h ago

Mojitos!!!

Simple Syrup - dissolve sugar in hot and chill it. 1/2 oz

Fresh Squeezed lime juice. 1 oz

Rum 2 oz

Mineral water (club soda for most of y'all) top off.

Muddled mint. 6-10 fresh leaves

Really is a great drink

#mojito #cocktail #alcohol #drink #iliketoeat

PugJesus 6h ago

Lidded glass tankard, Italy, 12th century AD

https://piefed.social/c/historyartifacts/p/2111517/lidded-glass-tankard-italy-12th-century-ad

caskfan 6h ago

@caskfan was drinking a #TuesdaysMild by #OtherworldBrewing at #TheForesters on Wednesday at 15:47 Served from cask, I rated it at 3.5 (good to great) #beer #alcohol #untappd #beersofmastodon

NieuwsJunkies.nl 8h ago

📰 Verdachte ongeluk Leontine Ruiters en Jada Borsato spoorloos na vlucht uit ziekenhuis

https://nieuwsjunkies.nl/artikel/1Hb3

🕞 15:18 | RTL Nieuws
🔸 #Alcohol #Dronken #Arrestatie #Diefstal #Spanje

Verdachte ongeluk Leontine Ruiters en Jada Borsato spoorloos na vlucht uit ziekenhuis

De bestuurder die betrokken was bij het ongeval met Jada Borsato (23) en Leontine Ruiters (58) reed onder invloed van alcohol in een gestolen auto met vervalste papieren. Dat bevestigt de Spaanse politie aan RTL Boulevard. De man wist na het ongeluk te ontsnappen en is nog altijd spoorloos. Er is een arrestatiebevel uitgevaardigd voor de dronken bestuurder die het ernstige ongeluk veroorzaakte.

RTL Boulevard

2 Medical News 14h ago

Reversible alterations of brain acetate metabolism associated with alcohol consumption

#Alcohol consumption elevates circulating acetate. Prior studies showed that acute alcohol reduces brain glucose uptake and increases #brain acetate oxidation. Previously we showed that heavy drinkers have elevated capacity to oxidize brain acetate. Here we repeat the study, adding individuals with alcohol use disorder (AUD). Four groups were enrolled. The analysis data set included Light Drinkers (LD, n = 13, female = 5), at-risk Heavy Drinkers (HD, n = 15, female = 7), AUD patients in long-term recovery (≥6 months; AUDLTR, n = 6, female = 1), and a separate group of AUD treatment-seekers (AUDTx, n = 12, female = 1) underwent medically supervised detoxification, scanned at ~1 week abstinence (n = 9) and 1 month (n = 10). Seven AUDTx participants successfully completed scans at both time points. We infused participants with [2-13C]acetate during magnetic resonance spectroscopy (MRS) of 13C-glutamate (Glu) and 13C-glutamine (Gln) in the brain, to measure the cerebral metabolic rate for acetate (CMRAc) and the neuronal tricarboxylic acid cycle relative to glutamate-glutamine neurotransmitter cycling (VtcaN/Vcycle; Energy Per Cycle: EPC). There was a group effect for CMRAc (p = 0.007) primarily owing to lower CMRAc in AUDTx at 1 week. Furthermore, higher CMRAc was observed among HD compared to LD participants, as previously reported. CMRAc was similar between the AUDLTR and HD groups. In a separate within-subject comparison among AUDTx participants, CMRAc increased after 1 month to levels similar to those of LD. EPC was similar among the groups, representing normal glutamate-glutamine cycling versus energetics. In summary, abstinence reversed the lower acetate oxidation in early AUD, showing that just a few weeks of recovery can normalize this metabolic abnormality.

https://www.nature.com/articles/s41386-026-02455-6

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#Alcohol #Brain

Reversible alterations of brain acetate metabolism associated with alcohol consumption - Neuropsychopharmacology

Alcohol consumption elevates circulating acetate. Prior studies showed that acute alcohol reduces brain glucose uptake and increases brain acetate oxidation. Previously we showed that heavy drinkers have elevated capacity to oxidize brain acetate. Here we repeat the study, adding individuals with alcohol use disorder (AUD). Four groups were enrolled. The analysis data set included Light Drinkers (LD, n = 13, female = 5), at-risk Heavy Drinkers (HD, n = 15, female = 7), AUD patients in long-term recovery (≥6 months; AUDLTR, n = 6, female = 1), and a separate group of AUD treatment-seekers (AUDTx, n = 12, female = 1) underwent medically supervised detoxification, scanned at ~1 week abstinence (n = 9) and 1 month (n = 10). Seven AUDTx participants successfully completed scans at both time points. We infused participants with [2-13C]acetate during magnetic resonance spectroscopy (MRS) of 13C-glutamate (Glu) and 13C-glutamine (Gln) in the brain, to measure the cerebral metabolic rate for acetate (CMRAc) and the neuronal tricarboxylic acid cycle relative to glutamate-glutamine neurotransmitter cycling (VtcaN/Vcycle; Energy Per Cycle: EPC). There was a group effect for CMRAc (p = 0.007) primarily owing to lower CMRAc in AUDTx at 1 week. Furthermore, higher CMRAc was observed among HD compared to LD participants, as previously reported. CMRAc was similar between the AUDLTR and HD groups. In a separate within-subject comparison among AUDTx participants, CMRAc increased after 1 month to levels similar to those of LD. EPC was similar among the groups, representing normal glutamate-glutamine cycling versus energetics. In summary, abstinence reversed the lower acetate oxidation in early AUD, showing that just a few weeks of recovery can normalize this metabolic abnormality.

Nature