Inhibition of the epigenetic co-activators p300/CBP prevents alveolar type 2 (AT2) cells from becoming trapped in a pathogenic "alveolar transitional cell state" (ATCS), thereby blocking the progression of idiopathic #pulmonary #fibrosis (#IPF ).
#RegenerativeMedicine #Epigenetics #Genetics #Medical #sflorg
https://www.sflorg.com/2026/02/gen02142601.html
Disrupting pathogenic cell states to combat pulmonary fibrosis

A key regulatory mechanism driving idiopathic pulmonary fibrosis (IPF) and identified a promising therapeutic strategy.

St. Luke’s – Global City launches a dedicated inhaler clinic to enhance pulmonary care

St. Luke’s Medical Center is proud to announce the launch of its Inhaler Clinic Service in Global City, designed to optimize the care of patients with pulmonary disorders such as asthma and chronic obstructive pulmonary disease (COPD).

The clinic aims to address a critical gap in respiratory care, including proper inhaler techniques.

Inhaler therapy remains the cornerstone of treatment for many pulmonary conditions. However, studies show that up to 94 percent of patients do not use their inhalers correctly, leading to poor symptom control, frequent exacerbations, and reduced quality of life.

https://twitter.com/tbcnewsph/status/1963819060485050703

Recognizing this, St. Luke’s has established a first-of-its-kind clinic focused on ensuring patients receive not only the proper medication but also the correct technique and support. It also offers coaching on the use and care of nebulizers.

The Inhaler Clinic has a multidisciplinary core team consisting of pulmonologists and respiratory therapists, and is built around four key goals:

● Assess and teach correct inhaler technique to ensure proper medication delivery and better disease control.

● Monitor adherence and treatment outcomes

Regular follow-ups allow the team to evaluate how well patients are using their prescribed therapies and to adjust management plans based on measurable progress.

● Identify and solve device-related problems

The clinic helps resolve issues such as improper device selection, technique errors, or device mismatch such as elderly patients, patients with arthritis, tremors or weakness, etc., supporting more personalized care.

● Empower patients and caregivers through education

Through structured teaching sessions, the clinic equips patients and families with the knowledge and confidence needed to manage respiratory conditions effectively at home.

By focusing on proper device use, personalized guidance, and continuous monitoring, the Inhaler Clinic aims to deliver tangible improvements that matter most to patients:

● Fewer asthma and COPD attacks

● Better medication absorption

● Reduced emergency room visits and hospitalizations

● Improved overall quality of life

Who should be referred to the Inhaler Clinic

Referral to the Inhaler Clinic is recommended for patients who may benefit from focused inhaler education and monitoring, including:

● Newly diagnosed patients with prescribed inhalers

● Individuals with persistent uncontrolled asthma or COPD

● Patients demonstrating recurrent inhaler errors

● Those on complex inhaler regimens (multiple devices or dosing schedules)

● Patients with device mismatch, such as elderly patients with limited hand coordination

● Patients or families expressing confusion or uncertainty

● Patients discharged with new inhaler prescriptions

As the first dedicated inhaler clinic in the Philippines, St. Luke’s sets a new standard in pulmonary care, offering patients a unique, comprehensive service to help them breathe easier.

For more information on referring patients to the Inhaler Clinic, contact the St. Luke’s Product Information Hub at 0947-9930471 / 0998-5822276 / 0939-9161805 / 0928-5200239.

#BUSINESS #Health #Insurance #latest #LIFESTYLE #lungs #news #Philippines #pulmonary #stLukes

New study from #MountSinai, out April 30. Studied ppl w/new heart issues who had mild or asymptomatic cases of COVID; biggest Long-COVID study to date, using heart imaging. Clear connection to several issues, stresses that "infection prevention is crucial".
#MaskUp #mask #respirator #CovidIsNotOver #LongCOVID #long #covid #face #shield #heart #lungs #brain #degraded #scar #tissue #chest #pain #shortness of #breath #fatigue #aorta #valve #disease #pulmonary #hypertension https://www.mountsinai.org/about/newsroom/2025/long-covid-may-cause-long-term-changes-in-the-heart-and-lungs-and-may-lead-to-cardiac-and-pulmonary-diseases
Long COVID May Cause Long-Term Changes in the Heart and Lungs and May Lead to Cardiac and Pulmonary Diseases

Mount Sinai study suggests COVID-19 infection should be considered a risk factor for future cardiopulmonary conditions

Mount Sinai Health System
#USA, #Texas Department of State Health Services is reporting the second #measles #death of a Texas resident in the ongoing #outbreak centered in the state's South Plains region. The #school-aged #child who tested positive for measles was hospitalized in #Lubbock and passed away on Thursday from what the child’s doctors described as measles #pulmonary #failure. The child was not vaccinated and had no reported underlying conditions. DOH: https://www.dshs.texas.gov/news-alerts/texas-announces-second-death-measles-outbreak

#Mpox #Hepatic and #Pulmonary #Lesions in #HIV / #Hepatitis B Virus Co-Infected Patient, #France

Source: Emerging Infectious Diseases Journal, AbstractWe report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had

Why don’t we issue refill canisters for inhalers?

We don’t need to replace every mouthpiece every month. Heck.

Wild anti-capitalist radicalism here: MAKE INHALER MOUTHPIECES INTERCHANGEABLE.

Cheaper for manufacturers and wholesalers and patients and our shared biosphere and —.

Ah smoked but Ah did nat inheyl. (“I smoked but I did not inhale.”)

#medicine #sustainable #sustainability #economy #medical #asthma #COPD #respiratory #cardio #pulmonary #inhalation

I’ve been infected with SARS-CoV-2 once I know of from June 2022 on:
the cause of the long covid that now defines my daily existence.
I suspect once more in March or April 2020 — but of fucking course, at that time the public could not access covid tests!

Every ignorant person who asserts they’ve never had it
could have been ASYMPTOMATIC
(that they noticed / wanted to notice / were in a position to consider it amid whatever went on in their lives at the time).

Absolutely no one can say they were never infected unless they were a
complete 24/7 no-cheat hermit
and / or covid testing
correctly at least once daily, *every single morning* from November 2020 to now.

And guess what else?
The (rapid lateral flow) antigen tests probably haven’t been updated to the latest strains in a while.

Good luck if you do have Covid 19 but can’t get time off work!
The (possibly expired) disposable test may not pick up new strains as reliably as older ones, which won’t be circulating as much as newer ones.

#covid #covid19 #pandemic #lockdown #LongCovidKids #longCovid #longHaulers #cardiovascular #CVD #heart #heartDisease #pulmonary #heartAttack #myocardialinfarction #etiology #transmission #infection #disease #CDC #NHS

Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection http://thorax.bmj.com/cgi/content/short/79/5/472?rss=1

Despite a high prevalence of fibrotic patterns (64%), pulmonary function, #grip strength, 6 min #walk distance and frailty normalised. Overall, #dyspnoea, #cough and #exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection http://thorax.bmj.com/cgi/content/short/thorax-2023-220370v1?rss=1

Overall, dyspnoea, cough and exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

#Rice is already known to contain more inorganic #arsenic than other cereals. Cooking rice with water containing more than 10 µg L-1 (parts per billion) inorganic arsenic amplifies the risk of arsenic exposure Long-term exposure to inorganic arsenic in water can cause serious health problems such as #cancers, #diabetes and #pulmonary and #cardiovascular diseases
#Environmental #NutritionalScience #sflorg
https://www.sflorg.com/2024/03/en03212402.html
Millions are at risk using high arsenic water for cooking

Rice is one of the major cereal crops in the world, contributing to the dietary energy and nutrition of more than half of the world's population