Mastodawn

"Physical activity results in the production of endocannabinoids and some studies have shown that exercise may slow the progression of Alzheimer’s disease."

"Cannabinoids remove plaque-forming Alzheimer’s proteins from brain cells – Preliminary lab studies at the Salk Institute find THC reduces beta amyloid proteins in human neurons"
https://www.salk.edu/news-release/cannabinoids-remove-plaque-forming-alzheimers-proteins-from-brain-cells/

A press release by the Salk institute on the paper:
"Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids", Currais et al. 2016
https://www.nature.com/articles/npjamd201612

#neuroscience #endocannabinoids #cannabinoids #AlzheimerDisease

Cannabinoids remove plaque-forming Alzheimer’s proteins from brain cells - Salk Institute for Biological Studies

LA JOLLA–Salk Institute scientists have found preliminary evidence that tetrahydrocannabinol (THC) and other compounds found in marijuana can promote the cellular removal of amyloid beta, a toxic protein associated with Alzheimer’s disease.

Salk Institute for Biological Studies

Psychedelic Institute Aug 22, 2025

https://psychedelicmentalhealth.net/spotlight-endocannabinoids-depression-and-treatment-resistance-perspectives-on-effective-therapeutic-interventions-rosa-et-al-2025/ Spotlight: Endocannabinoids, depression, and treatment resistance: Perspectives on effective therapeutic interventions (Rosa, et al, 2025) "glutamatergic and serotonergic agents such as ketamine, esketamine, and psychedelics, influence ECS components." #ketamine #psychedelics #psilocybin #lsd #depression #mentalhealth #psychedelicresearch #ketaminetherapy #psychedelictherapy #endocannabinoids #neuroscience #brains

Spotlight: Endocannabinoids, depression, and treatment resistance: Perspectives on effective therapeutic interventions (Rosa, et al, 2025)

"Ketamine and esketamine modulate CB1 receptors and other ECS targets, contributing to their rapid effects. Psilocybin restores 2-AG and enhances CB1 expression in mood-related brain regions, while LSD affects the broader endocannabinoidome in the prefrontal cortex and hippocampus."

Psychedelic Institute of Mental Health & Family Therapy

John Vaccaro (johniac)Dec 17, 2024

Attention-Worthy Links for December 17th, 2024

https://bit.ly/awl121724

#warming #global #accelerating #Copernicus #NOAA #1.6°C #ACES #bridges. #barracks #barriers #culverts #3D-Print #concrete #vaults #pre-eclampsia #mRNA #VEGF #Endocannabinoids #ABHD6 #hippocampus #waves #spindles #ripples #consolidation #dementia #Alzheimer's

Inbox | Substack

victorjavierlo Oct 30, 2024

🧬 Excited to share findings from a collaboration on #Alzheimer's! 🧬 Our team contributed RNA-seq analysis to explore how FAAH inactivation influences neuroinflammation and microglial function. This study reveals a paradox: while FAAH inactivation enhances microglial activity, it also escalates inflammation in 5xFAD AD mice. Results could point to FAAH as a therapeutic target in AD! #Neuroinflammation #Microglia #Endocannabinoids #RNAseq #ScienceCollab #bioinformatics

https://onlinelibrary.wiley.com/doi/10.1002/glia.24638

Show thread

Mycotropic Nov 12, 2023

@Catearthjustice

So they picked up 5 EWAS hits that are associated with EVER USE of cannabis which combines single use in high school (if reported) with lifetime daily use. Also >80% of their initial hits were in cigarette smokers. Okay, sure, they did a lot of work and combined lots of datasets but, my dude, do you really think that smoking pot once in your life causes associated genes to change expression? The #Endocannabinoids should have done that already shouldn't they? #SharedReceptors

Bud & Tender®Jun 13, 2023

🤍𝗛𝗮𝗽𝗽𝘆 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗔𝗹𝗯𝗶𝗻𝗶𝘀𝗺 𝗔𝘄𝗮𝗿𝗲𝗻𝗲𝘀𝘀 𝗗𝗮𝘆!🤍

Raise awareness on this day by learning "𝙏𝙝𝙚 𝙄𝙣𝙩𝙧𝙞𝙜𝙪𝙞𝙣𝙜 𝘾𝙤𝙣𝙣𝙚𝙘𝙩𝙞𝙤𝙣 𝘽𝙚𝙩𝙬𝙚𝙚𝙣 𝙀𝙣𝙙𝙤𝙘𝙖𝙣𝙣𝙖𝙗𝙞𝙣𝙤𝙞𝙙𝙨 𝙖𝙣𝙙 𝘼𝙡𝙗𝙞𝙣𝙞𝙨𝙢 𝙍𝙚𝙜𝙪𝙡𝙖𝙩𝙞𝙤𝙣...🌱👩‍🦳🧑‍🦳💚" - @budandtender

#albinism #awareness #day #cannabinoids #endocannabinoids #ECS #health #wellness

Bud & Tender®Jun 9, 2023

The Role of Endocannabinoids in Regulating Transverse Myelitis...💊

#cbd #wellness #medicine #myelitis #endocannabinoids

Bud & Tender®Jun 8, 2023

The Role of Endocannabinoids in Combating Brain Tumours...🧠
#cannabinoids #endocannabinoids #brain #braintumour #cancer #cbd #cbdoil

Bud & Tender®Jun 4, 2023

Happy National Cancer Survivor Day! 🙏 💕

The emerging research on endocannabinoids and their role in regulating cancer has opened up new avenues for understanding the complex mechanisms underlying cancer progression. Although more studies are needed to fully elucidate the therapeutic potential of targeting the endocannabinoid system, these findings offer hope for the development of novel cancer treatments.

#FeelGreatAgain #cancer #survival #cbd #cbdoil #endocannabinoids