Retrospective Chart Review Evaluating Efficacy and Tolerability of Ketamine Continuous Infusion for Cancer-Related Pain (Atayee, 2026) https://pubmed.ncbi.nlm.nih.gov/42132553/ Ketamine Continuous infusion produced a statistically significant and clinically meaningful reduction in cancer pain that increased over the course of infusion and was tolerated without identified psychoactive or circulatory adverse events. #ketamine #cancer #painmanagement #oncology #psychedelics #ketaminetherapy #ketaminesafety
Retrospective Chart Review Evaluating Efficacy and Tolerability of Ketamine Continuous Infusion for Cancer-Related Pain - PubMed

ContextKetamine is used to treat refractory cancer pain, but evidence for analgesic and opioid-sparing benefits remains mixed.ObjectiveThis study assessed the efficacy and tolerability of ketamine continuous infusion (CI) for cancer pain.MethodsThis retrospective analysis assessed adult patients adm …

PubMed
Cognitive effects of intravenous Ketamine in treatment-resistant depression: A systematic review (Chavigny, et al, 2026) https://pubmed.ncbi.nlm.nih.gov/42100880/ Subanesthetic IV ketamine appears to preserve and enhance specific cognitive functions in TRD, notably across processing speed, working memory, and executive control. These procognitive effects, particularly in executive control, may mediate ketamine's antisuicidal action. #ketamine #depression #suicide #mentalhealth #psychedelics #ketaminetherapy
Cognitive effects of intravenous Ketamine in treatment-resistant depression: A systematic review - PubMed

Intravenous (IV) low-dose ketamine has emerged as a promising treatment for patients with treatment-resistant depression (TRD). However, its impact on cognitive functioning remains unclear. This systematic review examines the cognitive and executive effects of IV ketamine in TRD, focusing on their r …

PubMed
Evidence in practice: implementing KAT in indigenous health services (Lovely, et al, 2026) https://pubmed.ncbi.nlm.nih.gov/42100772/ #ketamine #ketaminetherapy Findings demonstrated notable improvements in symptoms of #depression #anxiety and #ptsd with participants reporting increased emotional regulation and stronger cultural connections. #mentalhealth #indigenous #psychedelics
Evidence in practice: implementing KAT in indigenous health services - PubMed

Ketamine-Assisted Therapy (KAT) presents a promising alternative for addressing mental health challenges, particularly in treatment-resistant conditions, yet little exists in the literature guiding its implementation in an Indigenous context, for Indigenous participants, or describing culturally ada …

PubMed
HTTPS://psychedelicmentalhealth.net/ketamine-cancer/ #ketamine Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026) "These findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro. Further studies are warranted to elucidate the underlying molecular mechanisms and potential clinical implications. " #cancer #ketaminetherapy #psychedelics #pallliativecare #oncology
Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026)

"findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro."

Psychedelic Mental Health Institute
https://psychedelicmentalhealth.net/ketamine-cancer/ #ketamine Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026) "These findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro. Further studies are warranted to elucidate the underlying molecular mechanisms and potential clinical implications. " #cancer #colorectalcancer #ketaminetherapy #psychedelics #pallliativecare #oncology
Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026)

"findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro."

Psychedelic Mental Health Institute
Brazilian Psychiatric Association Guidelines for pharmacological treatment of Major Depressive Disorder: An overview of systematic reviews and meta-analyses - PubMed

These findings support a hierarchy of pharmacological strategies across different stages of MDD. Although consistent with international guidelines, their implementation should consider local healthcare context and resource availability.

PubMed
Cognitive Behavioral Mental Health & Psychedelics

Ketamine, Esketamine and Psychedelic Medicine Preparation, Support & Integration

Psychedelic Mental Health Institute
Personalized Multimodal and Opioid-Sparing Analgesia for Postoperative Pain Management: Enhancing Recovery and Addressing the Post-Discharge Gap
(Sezerano, et al, 2026) includes #ketamine and #cognitivebehavioraltherapy for #painmanagement https://pubmed.ncbi.nlm.nih.gov/42017149/ #ketaminesafety #ketaminetherapy
Personalized Multimodal and Opioid-Sparing Analgesia for Postoperative Pain Management: Enhancing Recovery and Addressing the Post-Discharge Gap - PubMed

Postoperative pain remains a persistent clinical challenge affecting more than 80% of surgical patients, driving prolonged hospitalization, delayed recovery, and progression to chronic postsurgical pain. Opioid-centered analgesia, despite its historical primacy, is constrained by dependence, toleran …

PubMed
The impact of ketamine on posttraumatic stress disorder (PTSD) symptomatology in trauma-exposed populations: a narrative review (Malik, et al, 2026) "Clinical trials suggest that a single intravenous infusion of ketamine (0.5 mg/kg) may significantly reduce PTSD symptoms within 24 hours” https://pubmed.ncbi.nlm.nih.gov/41922107/ #ptsd #ketamine #mentalhealth #psychedelics #ketaminetherapy
The impact of ketamine on posttraumatic stress disorder (PTSD) symptomatology in trauma-exposed populations: a narrative review - PubMed

Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used in trauma and emergency medicine for its rapid analgesic and sedative properties. While its efficacy in acute pain management is well established, concerns persist regarding its long-term psychological effects, particularly …

PubMed
Ketamine for negative and depressive symptoms in schizophrenia: the evidence so far (Diendorfer, et al, 2026 https://pubmed.ncbi.nlm.nih.gov/41918583/ #ketamine #psychedelics #depression #schizophrenia #ketaminetherapy #mentalhealth