The findings of this systematic review and meta-analysis suggest that single and repeated intravenous ketamine infusions are efficacious in reducing suicidal and depressive symptoms in patients with an MDE in the acute phase “Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode: A Systematic Review and Meta-Analysis” (Shim, et al, 2026) https://pubmed.ncbi.nlm.nih.gov/42090166/ #ketamine #depression #suicide #mentalhealth #psychedelics

https://pubmed.ncbi.nlm.nih.gov/42088180/ #ketamine #pain

HTTPS://psychedelicmentalhealth.net/ketamine-cancer/ #ketamine Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026) "These findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro. Further studies are warranted to elucidate the underlying molecular mechanisms and potential clinical implications. " #cancer #ketaminetherapy #psychedelics #pallliativecare #oncology

https://psychedelicmentalhealth.net/ketamine-cancer/ #ketamine Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026) "These findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro. Further studies are warranted to elucidate the underlying molecular mechanisms and potential clinical implications. " #cancer #colorectalcancer #ketaminetherapy #psychedelics #pallliativecare #oncology

How Scientists Cracked the Ketamine Code for Depression https://flip.it/zxzyVc #ketamine #psychedelics #mentalhealth

https://pubmed.ncbi.nlm.nih.gov/42066210/ #brazil #ketamine #ketaminetherapy #ketamina

https://pubmed.ncbi.nlm.nih.gov/42066082/ #ketamine TrkB/mGluR5 cross-talk underlies a synaptic metaplasticity mechanism of ketamine (2026) #brains #psychedelics #neuroscience

Ketamine-related neural changes in treatment-resistant depression: A multimodal synthesis of fMRI and PET studies (2026) findings suggest that ketamine-related effects were frequently reported in subcortical regions, alongside more distributed and context-dependent effects across cortical systems, including prefrontal and anterior cingulate regions. Network-level summaries further suggested involvement of default-mode, ventral attention, and visual systems. https://pubmed.ncbi.nlm.nih.gov/42061516/ #ketamine

https://psychedelicmentalhealth.net/psychedelic-therapy-cognitive-behavioral-therapy-ketamine-context-competencies/ #ketamine #psychedelic #Cognitivebehavioraltherapy Updating the literature review

Intranasal Ketamine for Existential Distress in Advanced Cancer (2026) https://pubmed.ncbi.nlm.nih.gov/42055096/ Intranasal ketamine was associated with clinically meaningful improvements in existential distress in individuals with advanced cancer being treated for depression. Ketamine may have relevance as a single agent for multidimensional distress in palliative care. #ketamine #psychedelics #palliativecare #mentalhealth #oncology