@SteveThompson

Nice skeptic article as any true science should be. Anything that links the 2011 Russo paper "Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects" is to be celebrated. Here is the link again in case somebody missed it.

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01238.x

Russo's paper has been cited 1,161 times and it deals with exogenous cannabinoids and terpenes, not just endogenous o made inside our body, as the 1998 Mechoulam research that originally proposed the entourage effect, or synergistic interaction between cannabinoids and terpenes.

I agree that right now due to obsolete prohibitions and sad profit-comes-first mentality the cannabis and hemp markets are a wild west of fake adultered product and unproven claims.

Yet since 2011 hundreds of studies have confirmed the entourage effect. Here is a small and incomplete collection of full spectrum extract papers 2004-2023.

https://www.cvresearch.info/full-spectrum-hemp-extracts-studies

Yet the article you linked to calls for more isolate testing... which complies to big pharmas love for patentable cheap to make single molecule symptom masking drugs.

I still agree with the article bottomline: governments should step up to the task instead of trusting research on this critical matter to profit-driven corporations. Mixed isolate cannabis pharmaceuticals have been in the market for a few years and proven their capabilities and limitations.

That is the case of Sativex, a 700 US$ 1:1 (thc:cbd) oral spray that controls some symptoms of MS yet fails to work for other conditions. Three separate studies ( Israeli, Brazilian and American) have since proven that full flower artisanal extracts are up to 6x more effective than expensive isolate preparations like Sativex
https://sensiseeds-com.translate.goog/es/blog/sativex-el-pionero-de-los-farmacos-derivados-del-cannabis/?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=es-419&_x_tr_pto=wapp

#Cannabis #cannabismedicinal #thc #thca #cbd #cbda #entourageeffect
#cannabislegal #Cannabisgesetz
#cannabislegalisierung #ganja
#maconha #weed #cannabisculture
#cannabisresearch #chronicillness
#ptsd #arthritis #stress #depression
#multiplesclerosis #ImmuneSystem

@copter_chief godspeed in your healing journey. Some words of advice:

Latest anticancer protocol calls for VERY GRADUAL dosage increase until reaching 5X the patient's weight in daily MG of COMBINED cannabinoids (not just THC). A 60 Kg patient should aim to consume and maintain 300 MG of daily cannabinoids. It should be in 3 daily doses of 100 MG in each meal to generate sufficient metabolic pressure. Start with 10-20 MG each night and gradually increase the dose/add the other doses over a couple of weeks to acclimate the body.

Prefer FECO (Full Extract Cannabis Oil) whose solvent has been slowly evaporated below 55°C or ROSIN oil (then partly decarbed in double boiler for 25 minutes at 90°C). Both contain up to 60% cannabinoids as well as some of the flower's original terpenes, which are lost in other forms of extraction. Not only are they more effective as anticancer agents, but their psychotropic effect is less severe.

I recommend a 1:1 balanced flower or a blend of two strains, one CBDA/CBD rich and other THCA/THC rich. If heated excessively or for too long, as per the original RSO recipe from 20 years, the acidic forms of THCA and CBDA are lost. Latest research has proven their anticancer, antiemetic, anxiolytic, antiinflammatory, and even neuroprotective effect through pathways different from THC/CBN.

RSO Rick Simpson Oil recipes overcook and leave nothing but THC and CBN (oxidized THC), requiring incapacitating megadoses of 2,000 MG/day. CBD-deficient "recreational" cannabis will lack modulation. Non #Stoner patients risk anxiety attacks/paranoia. Start low, increase slowly and use the right stuff.

Vaping doesn't generate enough metabolic pressure for anticancer effect. It will reduce nausea and pain quickly, but it's palliative. Smoking destroys half the medicine and generates nasty toxins.

#cannabismedicinal #cancer #Cannabis #marijuana
#thc #cbd #thca #cbda #weed
#entourageeffect #marihuana
#ganja #Cannabisgesetz #maconha
#corporategreed #solarpunk
#solarpunksunday #righttorepair