What are the mechanisms allowing #zebrafish to #regenerate their neurons after spinal cord injury? This study by Alberto Docampo-Seara, Catherine Becker, Thomas Becker &co shows that a protein in #microglia regulates regenerative #neurogenesis in multiple ways
This is the highlight of our early summer: On Friday 29 June 2026 we meet in a minisymposium world‑leading #microglia researchers like Laura Airas, Caroline Bergner, Christine Stadelmann, Susanne Wolf, Marco Prinz, and Steffen Jung. So exciting! #Immunology @utu.fi @aboakademi.bsky.social
🧠🚓 New paper on #microglia depletion: #CSF1R inhibition with #PLX5622 is not microglia-specific, it also depletes long-lived peripheral #macrophage populations. Could become important for interpreting #microglial #depletion experiments: Phenotypes after depletion or recovery may reflect broader macrophage niche perturbation, not microglia alone:
Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.
#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory
🧠 Alzheimer's & Microglia - Apr 2026
• Somatic cancer variants in microglia may drive Alzheimer's inflammation
• PAD2 in astrocytes worsens amyloid pathology via microglial activation
• Microglia uptake and release tau aggregates, seeding neuronal spread
• CK2 inhibition reduces glial inflammation and improves cognition
Clinicians and other mental health professionals will find the report informative for its cellular-level insights into depression. It notes two distinct cell types—neurons linked to mood and stress, and immune-related microglia—that behave differently in depression, pointing to disruptions in key brain systems and a biological basis for depressive states.
Article Title: For the first time, scientists pinpoint the brain cells behind depression
Link to Science Daily Mind-Brain News: https://nolinkpreview.com/www.sciencedaily.com/releases/2026/04/260423022010.htm
#DepressionBiology
#NeuralCellTypes
#Microglia
#MoodAndStress
#BrainNetworks
Loss of Smell Linked to Early Alzheimer’s Immune Activity
📰 Original title: Your nose could detect Alzheimer’s years before symptoms begin
🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅
View full AI summary: https://killbait.com/en/loss-of-smell-linked-to-early-alzheimers-immune-activity/?redirpost=5c3024a3-e4fe-4f6b-bcf5-2a9dd2d2ae35
Loss of Smell Linked to Early Alzheimer’s Immune Activity
📰 Original title: Your nose could detect Alzheimer’s years before symptoms begin
🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅
View full AI summary: https://killbait.com/en/loss-of-smell-linked-to-early-alzheimers-immune-activity/?redirpost=5c3024a3-e4fe-4f6b-bcf5-2a9dd2d2ae35
@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.
Huge congrats to Felix and all co-authors! 🥳
🧠 New paper from the @MaFu55 lab! 🥳
Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.
PLOS Biology
Yliopistobotti
Fabrizio Musacchio
Summarized Science
Psychotherapy Commission ACPE
KillBait News
KillBait