My previous lab, at Boston University, is searching for a new postdoc! Besides being an excellent and rigorous scientist, Mary Dunlop has an entirely deserved reputation of being an exceptional group leader. My three years in her lab have been the highlight of my scientific career so far, and if I am leading a research team one day, I will already be happy if I can make it half as kind, thoughtful and supportive as she made her group. I'd be delighted to answer any questions that potential candidates may have. Announcement below:

> My lab is hiring! We’re looking for a postdoctoral scholar in the area of optogenetic control, single-cell analysis, and gene expression dynamics in microbial systems. For more details see https://www.dunloplab.com/

#SystemsBiology #SyntheticBiology #GeneExpression #OptoGenetics #Microscopy #academia

🧪 Could digital modeling redefine how we grow CHO cells for biologics?

🔗 Wheels turning: CHO cell modeling moves into a digital biomanufacturing era. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.035

📚 CSBJ: https://www.csbj.org/

#Biomanufacturing #CHOCells #DigitalTwins #BiotechInnovation #DigitalBiomanufacturing #Bioprocessing #Biologics #CellCulture #GenomeScaleModels #SmartManufacturing #BiopharmaInnovation #SystemsBiology #Biotechnology #Bioinformatics

Virtual cells
https://udara.io/science/virtual-cells
https://news.ycombinator.com/item?id=44295725

Friggin' cool ! A synthetic cell phage cycle 👍️ | bioRxiv
https://mastodon.social/@persagen/114697081002977107

#SyntheticBiology #VirtualCells #DigitalTwins #SystemsBiology #virology

🔎 How can AI-powered tools help scientists uncover hidden connections in disease research?

🔗 Darling (v2.0): Mining disease-related databases for the detection of biomedical entity associations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.025

📚 CSBJ: https://www.csbj.org/

#AIinScience #BiomedicalTextMining #Genomics #PrecisionMedicine #Bioinformatics #OpenScience #BiomedicalResearch #BiomedicalAI #LiteratureMining #SystemsBiology #Omics #KnowledgeDiscovery

🧬 Are we overcomplicating proteomics—when a few unique sequences can tell the whole story?

🔗 Uniquome: Construction and decoding of a novel proteomic atlas that contains new peptide entities. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.027

📚 CSBJ: https://www.csbj.org/

#Proteomics #Uniquome #PeptideAtlas #Bioinformatics #PrecisionBiology #TranslationalResearch #SystemsBiology #MolecularBiology #PrecisionMedicine

Our (@kaletalab) new study uncovers multi-level metabolic disruptions in #IBD involving reduced #HostMicrobiomeInteractions.

Elevated tryptophan catabolism → NAD biosynthesis impaired.

Disrupted nitrogen homeostasis affects polyamine/glutathione metabolism.

Suppressed C1 cycle alters NAD/phospholipid profiles.

#MetabolicModeling predicts dietary interventions to restore #Microbiome balance.

Read and share: https://rdcu.be/eo7B3
#SystemsBiology #Microbiome #MultiOmics #CAU #UKSH #Kiel 

Lets talk #science for a change. We submitted a pre-print of the software I'm working on for my PhD thesis! Beautifully named manvr3d (aka, Manfred), we combine conventional #CellTracking software with #VirtualReality and a deep learning model to create a super fast human-in-the-loop system for tracking cells in 3D through time.

https://arxiv.org/abs/2505.03440

#Paper #ComputerScience #Biology #SystemsBiology

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