Bgee databaseDec 16
We are excited to announce a new training course on Bgee 🧬
Course: Gene Expression made Useful Easily: Tools and Database of Bgee
Date: Friday 29 May 2026
Taught by: the Bgee team (Frédéric Bastian and Marc Robinson-Rechavi)
Learn more: https://www.sib.swiss/training/course/20260529_BGEEL
#bioinformatics #training #RNAseq #singlecell #GeneExpression #bgee
@SIB @marcrr @fbastian
Gene Expression made Useful Easily: Tools and Database of Bgee

Attendance is free of charge; however, registration is mandatory. Overview Bgee is a curated database of gene expression in animals, including model s

Show threadBiohacking PathwayDec 16
#InheritedTrauma #Epigenetics #IntergenerationalTrauma #AncestralTrauma #MentalHealth #GeneExpression #Holocaust #911 #Science #wellbeingcoach #wellnessblog #wellnesswins #wellnessmatters #holisticwellbeing #Documentary https://mastodon.social/@biohackingpathway/115726650134542875
Dr Susi ArnottDec 12
Great case-study of #scienceinanemergency - studying changes in #geneexpression (once my research field!) is so important and fascinating, and wow - polar bears, the 'poster species' for #climatebreakdown! But let's not get distracted from the primary need to #decarbonise
https://www.theguardian.com/environment/2025/dec/12/changes-to-polar-bear-dna-could-help-them-adapt-to-global-heating-study-finds
Changes to polar bear DNA could help them adapt to global heating, study finds

Scientists say bears in southern Greenland differ genetically to those in the north, suggesting they could adjust

The Guardian
Show threadBiohacking PathwayDec 10
#motivation #geneexpression #biology #transform #health #wellness #mindset #genetics #science #selfimprovement #7days #inspiration https://mastodon.social/@biohackingpathway/115696863338274660
michaelNov 14

14-Nov-2025
The world’s oldest #RNA extracted from #woollyMammoth

https://www.eurekalert.org/news-releases/1105073 #science #fossils #ancientDNA #evolution #extinction #geneExpression #genome

The world’s oldest RNA extracted from woolly mammoth

Researchers from Stockholm University have – for the first time ever – managed to successfully isolate and sequence RNA molecules from Ice Age woolly mammoths. These RNA sequences are the oldest ever recovered and come from mammoth tissue preserved in the Siberian permafrost for nearly 40,000 years. The study, published in the journal Cell, shows that not only DNA and proteins, but also RNA, can be preserved for very long periods of time, and provide new insights into the biology of species that have long since become extinct.

EurekAlert!
Biohacking PathwayOct 25

Your Genes: The Piano Keys of Your Life

Unlock the secrets of your health! We explore how your exposome—lifestyle, environment, and experiences—influences your genes and overall well-being. Discover how your life shapes your health journey in this insightful podcast.

Follow @biohackingpathway for more⁣

#Exposome #Epigenetics #GeneExpression #Health #Lifestyle #Environment #Wellbeing #Podcast #Science #wellbeingcoaching #wellnessguide #wellnessvibes #biohack #biohacking #biohacker #HealthTips

The FSBIOct 23

New research on #Tilapia #nutrition! Incorporating germinated FabaBeans into #FishFeed enhances growth, reduces oxidative stress, and modulates #ImmuneResponse. Learn how it impacts #antioxidant activity and immune #GeneExpression in tilapia! doi.org/10.1111/jfb.70121 #JFB

http://doi.org/10.1111/jfb.70121

Show threadBiohacking PathwayOct 17
#CircadianRhythm #MetabolicHealth #SleepConsistency #HealthyEating #LightExposure #BiologyBasics #WellnessJourney #HealthTips #GeneExpression #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #BiologicalClock https://mastodon.social/@biohackingpathway/115391097630144004
Show threadKevin RussellOct 16

@compoundchem

You could get something looking like grapes.

Apples "have an especially profound amount of genetic variation", apples are heterozygous. Lots and lots of competing possible DNA expression and mutation.

https://www.nhpr.org/environment/2020-10-16/ask-sam-why-cant-i-get-the-same-type-of-apple-if-i-plant-an-apple-seed

#heterozygous #apple #dna #geneExpression

Ask Sam: Why Can't I Get The Same Type Of Apple If I Plant An Apple Seed?

Every other Friday on Morning Edition NHPR’s Sam Evans-Brown tracks down answers to questions about the environment and outdoors for our listeners in a…

NHPR
Cytology and GeneticsOct 16
Polymorphisms and Expression of Genes Associated with JAK/STAT Signaling in Patients with Myeloproliferative Neoplasm - #A20 #CYLD #myeloproliferativeneoplasms #SHP #STATs #HLA #genepolymorphisms #geneexpression #JAKSTATsignaling - https://link.springer.com/article/10.3103/S0095452725040061
Polymorphisms and Expression of Genes Associated with JAK/STAT Signaling in Patients with Myeloproliferative Neoplasm - Cytology and Genetics

Abstract Myeloproliferative neoplasms, encompassing essential thrombocythemia, primary myelofibrosis, and polycythemia vera, represent a subset of hematological disorders within the Philadelphia-negative subgroup. The molecular network involved in the JAK/STATs signaling pathway has been demonstrated involved in the genetic landscape of Myeloproliferative disorders in several studies. Deubiquitinating genes such as CYLD and A20 are known as negative regulators of immune reactions. In this study, we assessed the expression levels of CYLD, A20, SHPs, and STATs genes by q-PCR. Additionally, genotyping via Kompetitive Allele Specific PCR (KASP) was employed to discern the genotypes of 5 variants within the A20, JAK2, HLA, and OR10Q2P genes. Furthermore, levels of inflammatory cytokines and cancer antigen 125 (CA-125) were quantified using enzyme-linked immunosorbent assay (ELISA). Results showed that mRNA levels of CYLD, A20 and SHP-1 were significantly lower in all Myeloproliferative neoplasms patients, while expressions of SHP-2, STAT1 and STAT6 were significantly enhanced in Essential thrombocythemia patients when compared to controls. Concentrations of inflammatory cytokines IL-6, TNF-α, IL-1β as well as the cancer antigen protein CA-125 were elevated in Myeloproliferative neoplasms cases. Genotyping results explored that rs10974947 in JAK2, rs200878487 in A20, and rs2281389 in HLA had higher frequencies in PMF cases compared to controls. Importantly, two novel associations as our knowledge, between the variant HLA rs2281389 (p = 0.004, OR = 2.6, 95% CI = 1.36–4.85) and OR10Q2P rs12289961 – a LPXN-nearby variant (OR = 1.95, 95%CI = 1.01–3.75) with Polycythemia vera were detected in this studied population. These data suggested that A20, JAK2, HLA and LPXN genes may have important functions in disease phenotypes. Nevertheless, further functional studies on these genes should be carried out for a better understanding of Myeloproliferative neoplasms pathogenesis.

SpringerLink