Mastodawn

SMART (Single-Molecule Assay on Ribonucleic acid by Translated product) is an advanced in vitro selection platform designed to accelerate directed enzyme evolution. It significantly reduces the time and cost required to identify superior enzyme variants by tracking them at the single-molecule level.
#SyntheticBiology #MolecularBiology #Biochemistry #Biotechnology #sflorg
https://www.sflorg.com/2026/04/sybi04282601.html

Scientists pave the way for fast, cost-effective custom enzyme development

Enzymes are proteins that catalyze chemical reactions in living organisms

Scientific Frontline 13h ago

Exosomes containing signaling molecules derived from wild Scandinavian flatworms can significantly accelerate tissue repair and wound healing in human skin models.
#ChemicalBiology #RegenerativeMedicine #MolecularBiology #Therapeutics #sflorg
https://www.sflorg.com/2026/04/bio04282601.html

Wild flatworms heal wounds

The study suggests that signaling molecules from flatworms can accelerate the human body’s own healing processes

mymedschool 21h ago

Molecular mechanism of cancer metastasis and invasion USMLE
#USMLEStep1 #MedEd #Pathology #Oncology #Metastasis #CancerBiology #Microbiology #Step1Prep #HighYield #MedSchool #InfectiousDisease #MolecularBiology #FutureDoctor #StudyGram #MedTwitter #Anki #BoardExams #MedicalStudent #FirstAid #Medical

https://mymedschool.org/portfolio/u01-17-065-tissue-invasion-metastasis/?utm_source=mastodon&utm_medium=jetpack_social

U01.17.065 Cancer Pathogenesis: The Metastatic Cascade and Tissue Invasion

Master the steps of tissue invasion and metastasis (U01.17.065) for USMLE Step 1. Learn the molecular mechanisms of E-cadherin loss, basement membrane degradation, and the seed-and-soil hypothesis. High-yield guide on mymedschool.org.

mymedschool.org

mymedschool 1d ago

How cancer cells achieve replicative immortality telomerase USMLE

#USMLEStep1 #MedEd #Pathology #CancerBiology #Oncology #Telomerase #MolecularBiology #Step1Prep #HighYield #MedSchool #Genetics #CellBiology #FutureDoctor #StudyGram #MedTwitter #Anki #BoardExams #MedicalStudent #FirstAid #MedicalSch

https://mymedschool.org/portfolio/u01-17-064-replicative-potential-of-cancer-cells/?utm_source=mastodon&utm_medium=jetpack_social

U01.17.064 Replicative Potential of Cancer Cells: Telomerase and Immortality

Master the hallmarks of cancer (U01.17.064) for USMLE Step 1. Learn how cancer cells achieve replicative immortality through telomerase activation and the evasion of senescence. High-yield guide on mymedschool.org.

mymedschool.org

Scientific Frontline 1d ago

Setidegrasib is an investigational targeted therapy drug designed to attack and eliminate KRAS G12D, a critical cancer-driving protein responsible for advanced lung and pancreatic cancers.
#MolecularBiology #Pharmaceutical #Oncology #Cancer #sflorg
https://www.sflorg.com/2026/04/ongy04272602.html

Targeted therapy drug shows early promise against KRAS-driven lung and pancreatic cancers

The KRAS G12D protein has historically been considered extremely difficult to target due to a structural makeup

Scientific Frontline 1d ago

Researchers have captured the highest-resolution, multi-stage structural images to date of single-strand #DNA annealing. By observing Mgm101—an ancestral yeast protein that serves as a model for the human DNA repair protein RAD52—scientists have mapped the precise physical phases of the DNA repair process.
#MolecularBiology #Biology #Biochemistry #Oncology #sflorg
https://www.sflorg.com/2026/04/mbio04272601.html

Best snapshots yet of DNA repair protein relevant to BRCA mutations

Capturing multiple stages of process opens door to killing cancer cells

Scientific Frontline 1d ago

Polμ (Polymerase mu) is a crucial protein that facilitates DNA repair in macrophages during an immune response, ensuring the survival of these essential cells. By protecting innate immune cells from the genetic damage caused by their own pathogen-destroying mechanisms, Polμ enables effective tissue repair and limits chronic inflammation.
#Immunology #MolecularBiology #Physiology #sflorg
https://www.sflorg.com/2026/04/imgy04272601.html

Researchers identify a key protein in the inflammatory response to infections

The study shows, in animal models, that a deficiency of this protein compromises the survival of essential immune system cells.

Scientific Frontline 1d ago

The aggressiveness of squamous cell carcinomas (SCC), a common type of epithelial cancer, is determined not solely by the cancer cells themselves, but by the lipid metabolism of fibroblasts within the surrounding tumor microenvironment.
#Oncology #CellBiology #Biochemistry #MolecularBiology #Cancer #sflorg
https://www.sflorg.com/2026/04/ongy04272601.html