Mastodawn

Researchers have engineered a novel tumor-killing complex, designated NheA-O, by combining a naturally occurring soil bacterial protein with a fatty acid to target and destroy colorectal cancer cells.
#MolecularBiology #Oncology #Biochemistry #Microbiology #sflorg
https://www.sflorg.com/2026/04/mbio04222601.html

Researchers turn soil bacterial protein into potent cancer cell killer

An engineered bacterial protein can trigger a unique form of cancer cell death.

CSBJ 1d ago

🫧 Is there a point where hydration stops helping, and starts harming tissue integrity?

🔗 How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0050

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Collagen #Biomaterials #TissueEngineering #Cartilage #Biomechanics #BiomedicalEngineering #MolecularBiology #Biophysics #RegenerativeMedicine #Bioengineering

Scientific Frontline 1d ago

Biologic medications are highly complex therapeutic mixtures derived directly from living natural sources—such as human, animal, or microorganism cells—rather than being chemically synthesized.
#WhatIs #Pharmacology #Immunology #Biotechnology #MolecularBiology #Biomanufacturing #sflorg
https://www.sflorg.com/2026/04/wi04212601.html

What Is: Biologic Medication

Biologics have fundamentally redefined therapeutic intervention by conquering the "undruggable" frontier.

Scientific Frontline 2d ago

Epigenome regulators are specialized proteins bound to DNA that control gene expression not merely as simple on/off switches, but by producing distinct, uniquely patterned behaviors and expression dynamics for specific genes.
#Epigenetics #MolecularBiology #SyntheticBiology #CellularEngineering #sflorg
https://www.sflorg.com/2026/04/epig04202601.html

Study Finds Each Protein in the Epigenome Produces a Different Pattern of Gene Expression

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off

CSBJ 2d ago

🧬 What if disease isn’t written in DNA, but in how RNA is edited and spliced?

🔗 Long-Read Sequencing Reveals RNA Splicing Complexity in Human Diseases. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0052

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#RNASequencing #Genomics #Transcriptomics #PrecisionMedicine #MolecularBiology #Bioinformatics #NextGenSequencing #RNA #DNA

MostDiscussed 4d ago

In molecular biology, Human Accelerated Region 1 (Highly Accelerated Region 1, HAR1) is a segment of the human genome found on the long arm of chromosome 20. #MostDiscussed #MolecularBiology https://www.mostdiscussed.com/article/418043

Most Discussed 📖 - Human Accelerated Region 1

Scientific Frontline 6d ago

Infants who are exclusively breastfed for a minimum of three months display distinct, long-term DNA methylation marks in their blood on genes related to immunity and developmental processes.
#Epigenetics #MolecularBiology #Immunology #Pediatrics #sflorg
https://www.sflorg.com/2026/04/epig04162601.html

Exclusive breastfeeding linked to long-term changes in marks on DNA, found in blood

Babies who are exclusively breastfed for at least three months carry markers in their blood that differ from babies who are not breastfed

Scientific Frontline 6d ago

Plants adjust to fluctuating environmental temperatures by dynamically altering the expression of Rubisco, the critical and highly abundant protein responsible for fixing carbon during the first step of photosynthesis.
#Botany #MolecularBiology #Biochemistry #AgriculturalScience #sflorg
https://www.sflorg.com/2026/04/bot04162501.html

Temperature shifts change plant proteins powering photosynthesis

Plants adjust to temperature changes, in part, by switching the way they express the protein that performs the critical first step of photosynthesis

Scientific Frontline 6d ago

Cellular senescence is a biological stress response where cells cease dividing but do not die, instead lingering in tissue and emitting a toxic cocktail of inflammatory signals. In the liver, immune cells known as macrophages can enter this "zombie" state, continuously accumulating and driving the chronic inflammation associated with both aging and fatty liver disease.
#CellBiology #Immunology #Hepatology #Gerontology #MolecularBiology #sflorg
https://www.sflorg.com/2026/04/cbio04162602.html

UCLA scientists identify zombie immune cells as a driver of fatty liver disease, inflammation and aging

The study found that excess dietary cholesterol, not just aging alone, can push these immune cells into a permanently inflamed state, suggesting that

Scientific Frontline Apr 15

#MitoCatch is an advanced cellular delivery system designed to transplant healthy donor mitochondria directly into diseased or damaged cells. It acts as a targeted therapy to restore vital energy management in cells suffering from mitochondrial dysfunction.
#MolecularBiology #CellBiology #Neuroscience #MitochondrialMedicine #sflorg
https://www.sflorg.com/2026/04/mbio04152601.html

MitoCatch delivers healthy mitochondria to diseased cells

MitoCatch overcomes the long-standing biological obstacle of targeted delivery without triggering a detectable immune response