CSBJ6d ago

🤯 What if most “biological insights” are just mixed-up signals we never untangled?

🔗 Integrative Learning of Disentangled Representations from Single-Cell RNA-Sequencing Datasets. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0015

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SystemsBiology #Genomics #Bioinformatics #ComputationalBiology #AIinBiology #SingleCell #MachineLearning #DataScience #LifeSciences

CSBJMar 11

🧬 Can we map the cascade of gene activity that guides cells through differentiation?

🔗 Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis. Computational and Structural Biotechnology Journal (CSBJ). https://spj.science.org/doi/epdf/10.34133/csbj.0007

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SingleCell #Genomics #Bioinformatics #SystemsBiology #GeneExpression #ComputationalBiology

Summarized ScienceFeb 12

📊 Bioinformatics - Jan 2025

• Population-scale modeling maps the tumor immune microenvironment
• RNA–small molecule prediction advances structure-free drug discovery
• Improved microbiome analytics refine association testing

https://pir.sh/9OxdzbYdBl

#Bioinformatics #CancerGenomics #SystemsBiology

Bioinformatics Research Summary January 2026 - Summarized Science

Summary of key Bioinformatics publications highlighting major findings, clinical relevance, and emerging research trends.

Show threadbsmall2Feb 6
🧵
> Systems biology did not rise without skepticism. The great geneticist and Nobel-prize winning biologist Sydney Brenner once defined the field as "low input, high throughput, no output science." Brenner, a contemporary of Chomsky who also participated in the same symposium on AI, was equally skeptical about new systems approaches to understanding the brain...Brenner's catch-phrase.. is not far off from Chomsky's criticism of AI. An unlikely pair, systems biology and artificial intelligence...
https://www.theatlantic.com/technology/archive/2012/11/noam-chomsky-on-where-artificial-intelligence-went-wrong/261637/
#SydneyBrenner #SystemsBiology
Noam Chomsky: Where Artificial Intelligence Went Wrong

An extended conversation with the legendary linguist

The Atlantic
de.NBI & ELIXIR GermanyFeb 3
🌏 @deNBI delivers training across the globe! Tomorrow, we're in Auckland 🇳🇿 for a @COPASI workshop at HARMONY 2026.
📅 Feb 4, 2026 | ⏰ 9:05–10:30 NZDT
🔬 Learn how to model, simulate, and analyze biochemical reaction networks with COPASI
🌐 More info:
https://www.denbi.de/training-courses-2026/2026-exploring-new-features-of-copasi
#COPASI #Bioinformatics #SystemsBiology #Modeling #Auckland #HARMONY2026 #deNBI #LifeSciences #Training #QuantitativeBiology
Scientific FrontlineJan 27
#Bacterial #plasmids utilize two distinct survival strategies—stealth and manipulation—to drive a "stealth-first" mechanism where #antimicrobial resistance genes are initially acquired by stealthy plasmids before being rapidly disseminated by manipulative ones.
#Biology #MolecularBiology #Bioinformatics #SystemsBiology #sflorg
https://www.sflorg.com/2026/01/bio01272601.html
Stealth and manipulation: Strategies of bacterial plasmids

Computational analysis exposes patterns of antimicrobial resistance spread

jobRxivJan 5

Lead Bioinformatician
Arinale Biosciences, Inc.

We are seeking a lead bioinformatician to establish robust interpretative frameworks for novel NGS-based assays.

See the full job description on jobRxiv: https://jobrxiv.org/job/arinale-biosciences-inc-27778-lead-bioinformatician/

#bioinformatics #BulkRNAsequencing #computationalbiology #DNAsequencing #systemsbiology #ScienceJobs #hiring #research
https://jobrxiv.org/job/arinale-biosciences-inc-27778-lead-bioinformatician/?fsp_sid=7697

Lead Bioinformatician

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
Show threadManlio De DomenicoDec 16
I feel in debt for the amazing discussions I had over 3 years with colleagues, too many to list here (but listed in the acks!) #ComplexSystems #NetworkScience #SystemsBiology #Evolution #NonEquilibrium #Evolvability 👉 Paper: iopscience.iop.org/article/10.1... 8/
Academic EuropeDec 11

Job Alert

Postdoctoral Researcher in Inter-organ Communication between Liver and Heart  

Deadline: 2026-01-07
Location: Germany, Heidelberg

https://www.academiceurope.com/ads/postdoctoral-researcher-in-inter-organ-communication-between-liver-and-heart/

#hiring #PhD #biochemistry #systemsbiology #bioinformatics #lifescience #hiring #proteomics #postdoc

CSBJNov 21

🧬 Can combining LLMs with full-length RNA isoforms unlock hidden cellular diversity?

🔗 Advancing automated cell type annotation with large language models and single-cell isoform sequencing. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.008

📚 CSBJ: https://www.csbj.org/

#LargeLanguageModels #Genomics #CellBiology #SingleCellRNASequencing #AlternativeSplicing #LLMs #SystemsBiology