#Vermont State Senator Samuel #Douglass will resign after participating in racist Young Republican group chat. | My Nazi Senator.
#vtdems #vtpol
> The Vermont state senator who’s been under #pressure to resign since revelations surfaced this week of his participation in a racist group chat announced Friday evening that he’s leaving public office.
The dissipation mechanisms in weakly collisional plasmas have been a longstanding topic of investigation, where significant progress has been made in recent years. A recent promising development is the use of the "scale-filtered" Vlasov-Maxwell equations to fully quantify the scale-by-scale energy balance, a feature that was absent when using fluid models in kinetic plasmas. In particular, this method reveals that the energy transfer in kinetic scales is fully accounted for by the scale-filtered pressure-strain interaction. Despite this progress, the influence of ion-electron thermal disequilibrium on the kinetic-scale energy budget remains poorly understood. Using two-dimensional fully kinetic particle-in-cell simulations of decaying plasma turbulence, we systematically investigate the pressure-strain interaction and its components at sub-ion scales by varying electron-to-ion temperature ratios. Our analysis focuses on three key ingredients of the pressure-strain interaction: the normal and shear components of Pi-D and pressure dilatation. Our results demonstrate that the scale-filtered pressure-strain interaction is dominated by scale-filtered Pi-D across the kinetic range, with the shear component consistently providing the dominant contribution. We find that the scale-filtered normal and shear contributions of Pi-D exhibit persistent anticorrelation and opposite signs across all kinetic scales. We also discover that the amplitude of both anisotropic components for each species scales directly with their temperature and inversely with the temperature of the other species, while the scale-filtered pressure dilatation remains negligible compared to the Pi-D terms but shows enhanced compressibility effects as plasma temperatures decrease. We discuss the implications of these findings in thermally non-equilibrated plasmas, such as in the turbulent magnetosheath and solar wind.
Background: Lipid peroxidation and iron accumulation are hallmarks of ferroptosis, a form of cell death characterized by iron-dependent oxidative damage to cellular membranes. However, the molecular link between lipid peroxidation and iron overload in the execution of ferroptosis remains elusive. Moreover, the pathophysiological implications of the interaction between lipid peroxidation and iron overload in cardiac homeostasis and remodeling are also unknown. Methods: We assessed the role of lipid peroxidation in mediating cardiac iron overload and ferroptosis using genetic mouse models. We also performed molecular and cellular biology studies to elucidate the mechanisms by which lipid peroxidation regulates iron homeostasis and ferroptosis signaling in cardiomyocytes. Results: Cardiomyocyte-specific ablation of Gpx4 (glutathione peroxidase 4), a key suppressor of lipid peroxidation, promoted iron overload and ferroptosis in the heart, leading to dilated cardiomyopathy. Mice with heterozygous Gpx4 knockout were also predisposed to adverse cardiac remodeling and dysfunction following pressure overload. Mechanistically, elevated lipid peroxidation due to GPX4 inactivation intrinsically induced iron overload by promoting the nuclear export of Bach1 and subsequent induction of heme oxygenase-1 (HO-1). Genetic and pharmacologic inhibition of HO-1 markedly attenuated iron overload and ferroptosis in cardiomyocytes and rescued dilated cardiomyopathy associated with Gpx4 deficiency. Moreover, we identified HO-1 mitochondrial translocation as a key mechanism driving mitochondrial iron overload and ferroptosis. Targeted inhibition of mitochondrial iron overload or lipid peroxidation abrogated cardiac ferroptosis and pathological remodeling induced by Gpx4 deficiency. Conclusions: These findings identified a mechanistic link between lipid peroxidation and iron overload via the Bach1-HO-1 signaling pathway, revealing new regulators and molecular targets for cardiac ferroptosis. ### Competing Interest Statement The authors have declared no competing interest.
**In America, we don’t put up with would-be kings.** 📍 Where: Father Duffy Square, 47th st. and Broadway 📅 When: 11:00 AM ET, October 18, 2025 NOTE: this will be a march, not a rally! Enter from the northern side, and we recommend using subway stops on 47th-50th streets Our peaceful movement is only getting bigger and stronger. “NO KINGS” is more than just a slogan—it’s the foundation our nation was built upon. Born in the streets, carried by millions in chants and on posters, it echoes from city blocks to rural town squares, uniting people across this country to fight dictatorship together. The president thinks his rule is absolute. But in America, we don’t have kings, and we won’t back down against chaos, corruption, and cruelty. Grow our movement and join us. _A core principle behind all No Kings events is a commitment to nonviolent action. We expect all participants to seek to de-escalate any potential confrontation with those who disagree with our values and to act lawfully at these events. Weapons of any kind, including those legally permitted, should not be brought to events._
Yknow as I get older and my illnesses pile up, I’m very aware of my mortality. And while on a fundamental “awareness go poof” level I’m not really afraid of the concept of #death, as I have experienced awareness without self and know all is one, in a cosmic sense (It’s kinda old hat for me), I still have fears.
But my fear is not of the nothingness most westerners imagine.
No, when the time gets closer, what terrifies me as an #ActuallyAutistic person are more questions of pain, hospitalization, the internalized feelings that I’m not doing enough to keep myself healthy (I have NEVER experienced this delusion called “health”), and that because of this, when I go it will be “my fault.”
What scares me as an autistic person with #chronicillness isn’t say, the fear of dying of cancer (assuming that’s the way I go, which is a hypothetical); it’s the fear and #anxiety of being forced to act, to fight —when I’m too overwhelmed and sick to do so— simply out of a sense of obligation or societal pressure.
I’m not sure if it’s a thing that allistic (non-autistic) people can understand, but #pressure to perform will only cause me to #shutdown. It’s the main reason I rarely get to my doc appointments in the first place—it’s absolutely exhausting.
Now don’t get me wrong, I’m not talking about intentional self harm here (I respect myself too much to waste energy on making matters worse), but more the recognition that I’m not a fighter by nature, and as someone who deals with both #chronicfatigue (#MECFS) and cognitive and sensory overload, sometimes just survival itself feels like a burden and an obligation.
It’s why I sleep so much (when I CAN sleep).
So if I feel that way now, when I have pretty shitty —but still manageable #qualityoflife— I don’t think it should be too far beyond the obvious that at SOME point it’ll make more sense to just let go and float where the currents of life take me instead of struggling. Hell, on some levels I’ve already been doing that for years.
So I guess the tl;dr takeaway of all this rambling is that my biggest fear, the thing I’m terrified most of, is being forced or pressured to perform beyond my neurological capabilities, “OR ELSE!”. I’m afraid to be stuck in a hospital with bad fluorescent lighting, to feel a constant IV in my arm that restricts my movement and makes me feel cold inside. I’m afraid of the thought of enduring chemotherapy or dialysis or whatever other hellish torture allistic humans have devised in order to “help” people by prolonging a life whose quality —if not already nonexistent— will be destroyed in the process, all in the name of survival.
Those are my fears, and I feel a bit lighter (but mostly awkward), having talked about them. If anyone out there can actually understand where I’m coming from, please let me know—And remember these three affirmations of mine for when that survival-obligation performance anxiety paralyzes your mind:
1: No doctor in the history of mankind has ever SAVED a life, but merely PROLONGED it.
2: Perhaps the most salient irony of life is the fact that no one ever gets out alive.
And lastly,
3. It’s permitted to not be immortal; no one will ever live up to that standard—and that’s ok.
Thank you for your time and support. 
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