HackadayTesting the Pressure Limits for Glass in Water Cooling Blocks
13Testing the Pressure Limits for Glass in Water Cooling Blocks https://hackaday.com/2026/02/22/testing-the-pressure-limits-for-glass-in-water-cooling-blocks/
#Hardware #Pressure #Watercooling
#Hardware #Pressure #Watercooling
Rxiv mechanobio📰 "Interactions of Phototropism and Gravitropism in Cyanobacteria"
https://www.biorxiv.org/content/10.64898/2026.02.21.707229v1?rss=1 #Pressure #Cell
https://www.biorxiv.org/content/10.64898/2026.02.21.707229v1?rss=1 #Pressure #Cell
Interactions of Phototropism and Gravitropism in Cyanobacteria
While gene expression in bacteria has been shown to be affected by near-zero or extremely high gravity, a mechanism has not been established to date. In larger organisms, gravity-sensing mechanisms usually rely on a dense body applying directional pressure which can be detected by the cell. Herein we demonstrate a means of observing the effect of gravity on cyanobacteria by differential expression of native pigments in response to both gravity and light. We observe that in the cyanobacterium Synechococcus sp. PCC 7002, the distribution of pigmentation within the cell, and across cell colonies, is regulated by combined directional sensing of incoming light, adhesion to a surface via extracellular matrix, and applied external force, including the normal force of gravity applied to the cell. Cells grown on a substrate orient their thylakoids on the cell faces proximal and distal to the substrate and locate both chlorophyll and phycobilins in both of these membrane regions; phycobilins are primarily targeted to the membrane region nearest to the light source, while chlorophyll is preferentially expressed in the region opposite the overall external force applied to the cell. The mechanism for distribution of pigments appears to be regulated by presence of polyphosphate bodies within the cell, and removal of polyphosphate negates the cell's ability to sense external forces. Furthermore, colonial morphology is affected by application of force, with cells responding to the secretions of other cells along a gradient along the expected response to shading. These results represent a critical step toward understanding basal phototrophic regulatory mechanisms of light use and demonstrate the first known intracellular directional gravity response mechanism in a prokaryote. ### Competing Interest Statement The authors have declared no competing interest. United States Department of Energy, https://ror.org/01bj3aw27, DE-SC0019306
📰 "Collagen IV of basement membrane: V. Bromide-mediated sulfilimine bonds interlock the quaternary structure of NC1-hexamer of scaffolds enabling metazoan evolution."
https://www.biorxiv.org/content/10.64898/2026.02.20.707065v1?rss=1 #Pressure #Cell
https://www.biorxiv.org/content/10.64898/2026.02.20.707065v1?rss=1 #Pressure #Cell
Collagen IV of basement membrane: V. Bromide-mediated sulfilimine bonds interlock the quaternary structure of NC1-hexamer of scaffolds enabling metazoan evolution.
Collagen-IV (Col-IV) scaffolds, a primordial basement membrane component, enabled animal multicellularity, evolution and adaptation. These scaffolds provide tensile strength and tether macromolecules, forming supramolecular complexes that interact with cell-surface receptors and influence cell-behavior. Triple-helical Col-IV protomers, composed of three αchains, with a trimeric globular NC1-domain at the C-terminus, oligomerize forming a NC1-hexamer structure that connects adjoining protomers of Col-IVα121, Col-IVα556α121, and Col-IVα345 scaffolds. Hexamer formation and stability are driven by the extracellular chloride concentration "chloride pressure". Hexamer structure is reinforced by six sulfilimine bonds forming covalent crosslinks that weld together trimeric NC1-domains of adjoining protomers. We recently found evidence that sulfilimine bonds, independent of chloride, stabilize the quaternary structure of the Col-IVα345 hexamer of the Col-IVα345 scaffold. Here, we sought to determine whether this function also pertains to the Col-IVα121 scaffold that occurs ubiquitously across the animal kingdom, and whether bromine, a cofactor of peroxidasin in bond formation, are evolutionary conserved. We found that sulfilimine bonds stabilized the quaternary structure of the Col-IVα121 hexamer of bovine, mouse and a basal cnidarian, Nematostella vectensis, and that the mechanism of bond formation mediated by peroxidasin and bromide is evolutionary conserved. Analyses of the crystal structure of the NC1-hexamer revealed that sulfilimine bonds covalently fasten a clasp-motif across the trimer-trimer interface, interlocking the domain-swapping region of neighboring subunits, which reinforces the hexamer quaternary structure imposed by chloride conformational constraints. Collectively, our findings reveal that the sulfilimine-bond reinforcement is a critical event in Col-IV scaffold assembly enabling multicellularity, evolution and adaptation of metazoans, beginning with ancient cnidarians. ### Competing Interest Statement Billy G. Hudson is an equity stockholder in Sulfilatec NIH, R01DK018381, R01DK131101, R25DK096999
Moviz Ark'Pressure' Trailer Finds Brendan Fraser & Andrew Scott in a High-Stakes WWII Drama!! Check It Out!! #AndrewScott, #BrendanFraser, #ChrisMessina, #DamianLewis, #KerryCondon, #Pressure, #ConONeill, #TobyWilliams, #DanielQuinnToyes, #TraffordLeighMallory, #HenryAshton
‘Pressure’ Trailer Finds Brendan Fraser & Andrew Scott in a High-Stakes WWII Drama!! Check It Out!!
Synopsis – In the tense 72 hours before D-Day, the fate of the world hangs in the balance. General Dwight D. Eisenhower and Captain James Stagg face an impossible choice–launch the most…
Follow GOLFhttps://www.fogolf.com/1171771/when-the-tee-shot-is-high-pressure/ When the Tee Shot is High Pressure #Golf #GolfBalls #GolfBallsVideos #GolfBallsVlog #GolfBallsYouTube #GolfEquipment #GolfEquipmentVideos #GolfEquipmentVlog #GolfEquipmentYouTube #GolfShorts #GolfTee #GolfTees #GolfTeesVideos #GolfTeesVlog #GolfTeesYouTube #High #livgolf #pga #pressure #Shot #tee
📰 "Growing microalga Neochloris oleoabundans in rocking and floating plastic bag photobioreactors"
https://www.biorxiv.org/content/10.64898/2026.02.18.702949v1?rss=1 #Pressure #Cell
https://www.biorxiv.org/content/10.64898/2026.02.18.702949v1?rss=1 #Pressure #Cell
Growing microalga Neochloris oleoabundans in rocking and floating plastic bag photobioreactors
This paper evaluated and compared the relative microalgal biomass accumulation of rocking, floating, and stationary bag photobioreactors. Microalga Neochloris oleoabundans was grown in these photobioreactors in batch mode for 24 days under illumination. The 50 L plastic bags (cell suspension volume 25 L) were placed on the surface of a rocking platform, an artificial pond or a stationary platform. In the pond, waves were generated by electrical fans which shake and mix microalgal cells within the plastic bags. The bags were supplied with 5% CO2 in air under elevated pressure inside of the bags. The rocking bag method significantly increased biomass yields to approximately 3-4 g/ L, as compared to 0.16 g/L in the floating photobioreactor and only 0.03 g /L in the stationary type photobioreactor. ### Competing Interest Statement The authors have declared no competing interest. U.S. National Science Foundation, https://ror.org/021nxhr62, 0821571
Phil EdwardsPressure – Watch Brendan Fraser and Andrew Scott in the trailer for the new World War II drama https://www.liveforfilm.com/2026/02/19/pressure-watch-brendan-fraser-and-andrew-scott-in-the-trailer-for-the-new-world-war-ii-drama/
#Pressure #BrendanFraser #AndrewScott #KerryCondon #film #WWII #DDay #DwightDEisenhower
DeadlineBrendan Fraser And Andrew Scott Face Weather Worries For D-Day Launch In ‘Pressure’ Trailer
#News #Trailers #AndrewScott #BrendanFraser #FocusFeatures #KerryCondon #Pressure
https://deadline.com/2026/02/pressure-trailer-brendan-fraser-andrew-scott-d-day-weather-1236729597/
IndieWire‘Pressure’ Trailer: Brendan Fraser Grapples with the Weight of D-Day as a Snarling General Eisenhower
#IndieWire #News #Trailers #BrendanFraser #Eisenhower #Film #Pressure
