MedSciPolApr 27, 2025

https://www.cbc.ca/news/canada/hamilton/hamilton-mcmaster-university-post-covid-19-guidelines-1.7494976
"Researchers at McMaster University say they've created Canada's first-ever comprehensive guidelines for diagnosing, managing, preventing, and treating post COVID-19 condition (PCC), more commonly known as long COVID."

https://canpcc.ca/home/

mit Infos für
Die Öffentlichkeit:
https://canpcc.ca/resources/#tab-content-patients-and-general-public

Medizinisches Fachpersonal:
https://canpcc.ca/resources/#tab-content-ov

Und für Menschen in politischer Entscheidungsverantwortung:
https://canpcc.ca/resources/policymakers/

#LongCovid #PostCovidCondition

McMaster University researchers create guidelines to help COVID-19 longhaulers | CBC News

Researchers at McMaster University say they’ve created Canada’s first-ever comprehensive guidelines for diagnosing, managing, preventing, and treating post COVID-19 condition (PCC), more commonly known as long COVID.

CBC
Show threadChristophe VeltsosSep 10, 2024
Here's the link to the piece in The Lancet that is referenced in the thread above: SARS-CoV-2 antivirals and post-COVID-19 condition - The Lancet Infectious Diseases www.thelancet.com/journals/lan... #PostCovidCondition #PCC #LongCovid #Antivirals

SARS-CoV-2 antivirals and post...
Tom KindlonSep 6, 2024

New review from Germany:

Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations & immunometabolic interactions in #postCOVIDcondition & #MEcfs

https://link.springer.com/article/10.1007/s15010-024-02386-8

Hashtags:
@longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC #COVIDBrain
#PEM @mecfs_de @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #PostExertionalMalaise

Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome - Infection

Background A considerable number of patients who contracted SARS-CoV-2 are affected by persistent multi-systemic symptoms, referred to as Post-COVID Condition (PCC). Post-exertional malaise (PEM) has been recognized as one of the most frequent manifestations of PCC and is a diagnostic criterion of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Yet, its underlying pathomechanisms remain poorly elucidated. Purpose and methods In this review, we describe current evidence indicating that key pathophysiological features of PCC and ME/CFS are involved in physical activity-induced PEM. Results Upon physical activity, affected patients exhibit a reduced systemic oxygen extraction and oxidative phosphorylation capacity. Accumulating evidence suggests that these are mediated by dysfunctions in mitochondrial capacities and microcirculation that are maintained by latent immune activation, conjointly impairing peripheral bioenergetics. Aggravating deficits in tissue perfusion and oxygen utilization during activities cause exertional intolerance that are frequently accompanied by tachycardia, dyspnea, early cessation of activity and elicit downstream metabolic effects. The accumulation of molecules such as lactate, reactive oxygen species or prostaglandins might trigger local and systemic immune activation. Subsequent intensification of bioenergetic inflexibilities, muscular ionic disturbances and modulation of central nervous system functions can lead to an exacerbation of existing pathologies and symptoms.

SpringerLink
Show threadTom KindlonApr 3, 2024

2/

"We have found 13 differentially expressed genes associated with PCC [#PostCovidCondition ]. Enriched pathways were related to interferon-signalling and anti-viral immune processes”

#LCKids #LongCovidKids @longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #CovidBrain @auscovid19

Show threadTom KindlonApr 2, 2024

3/

“(Contd) We also demonstrated that men and women suffering from PCC must be considered separately. Therefore, the variability in PCC must be taken in regard together with sex-specific differences."

#PostCovidCondition #CovidLong @longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #CovidBrain @auscovid19

Show threadTom KindlonNov 26, 2023

2/

"A similar pattern of HRV [heart rate variability] and baroreflex failure with signs of a pathological acceleration of age-dependant dysautonomia was identified in ME/CFS and PCC [#PostCovidCondition]”

@mecfs #MEcfs #CFS #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MyalgicE #MyE #ME #millionsmissing #CFSME #CFIDS
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 #CovidIsNotOver #CovidBrain

Tom KindlonNov 15, 2023

Physical exertion worsens symptoms in patients with #postCOVID condition : Post-exertional malaise in patients with #postCOVIDcondition

https://www.scienceopen.com/document/read?vid=6ebbad1a-4c23-4323-b20c-e57a346ce9f9

“The slogan 'Exercise is Medicine' does not apply to all patients with post-#COVID condition. A personalized approach aimed at preventing post-exertional malaise appears to be the right approach for this patient population for now"

1/
@longcovid
#LongCovid #PwLC #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers

<b>Physical exertion worsens symptoms in patients with post-COVID condition</b> : Post-exertional malaise in patients with post-COVID condition

<p class="first" dir="auto" id="d13794844e177"> <i>Patients with post-</i>COVID <i>condition suffer from fatigue, limited exercise capacity, and post-exertional malaise. Post-exertional malaise is the worsening of symptoms after physical or mental exertion, which reduces the efficacy of most forms of rehabilitation. This article presents the current understanding in the pathophysiology of post-COVID condition, particularly the underlying causes of post-exertional malaise. </i> </p>

ScienceOpen
LongCovidKidsMar 14, 2023

Sammie McFarland CEO & Founder LCK talks to Dan Walker and Ruth Liptrot about two families who were facing child protection proceedings because Long Covid is poorly understood and how the charity helped.

#LongCovidKids #LongCovid #Children #ShapingUs #Childhood #longcovidawarenessday #postcovidcondition #postcovidsyndrome #covidlonghaulers

LongCovidKidsMar 13, 2023

‘Nearly 1/4 of pediatric survivors suffered multisystem long COVID, even at 1 year after infection. Ongoing monitoring, comprehensive prevention and intervention is warranted for pediatric survivors, especially for individuals’

Multiple symptoms and multi-system involvement were reported.

Link in bio to read the paper.

#longcovidkids #longcovid #children #postcovidcondition #postcovidsyndrome #kids #childhealth

https://www.sciencedirect.com/science/article/pii/S1876034123000710

TypomumFeb 5, 2023

The fears among those refusing “vaccinated” blood include that mRNA-based vaccines can genetically modify humans, that the unvaccinated can get “vaccinated” via a blood transfusion, that the pandemic itself is a political hoax and that people who have chosen to be vaccinated “are in some way inferior.”

#BringBackMasks #CovidIsNotOver
#CovidIsAirborne
#WearAMask
#N95
#CovidIsReal
#COVIDVaccine
#Covid19
#postcovidcondition
#LongCovid
#FreshAir
#BloodTransfusion

http://bitly.ws/zMBV

COVID vaccine skeptics are asking Canadian hospitals for unvaccinated blood

Some people have refused blood for themselves, or a child, because of unfounded fears of blood 'tainted' by COVID vaccines.

National Post