Paul Houle21h ago

💦 Sperm microRNAs may enable transmission of exercise benefits from fathers to children

https://medicalxpress.com/news/2025-10-sperm-micrornas-enable-transmission-benefits.html

#sperm #microrna #rna #inheritance #biology #men #fathers #exercise #epigenetics #health

Sperm microRNAs may enable transmission of exercise benefits from fathers to children

In a recent study published in Cell Metabolism, a research paper provides the first evidence that sperm microRNAs act as carriers of epigenetic information, enabling the intergenerational transmission of paternal exercise capacity and metabolic health, thereby exerting profound effects on offspring development.

Medical Xpress
Scienza et MagiaOct 15

L'allenamento del padre migliora la salute dei figli. L'eredità nel movimento, scoperto il meccanismo molecolare che permette di trasmettere i benefici dell'attività fisica alla prole. La chiave è nei microRna presenti negli spermatozoi, che agiscono come interruttori genetici migliorando resistenza e metabolismo. Che lo stile di vita dei genitori influenzi la...

#allenamento #epigenetica #geniereditari #metabolismo #microrna #mitocondri #NCoR1 #spermatozoi

https://scienzamagia.eu/sociale-collettivita/lallenamento-del-padre-migliora-la-salute-dei-figli/

News BeepAug 11

Delphinidin upregulates microRNA-let-7b expression through family with sequence similarity 222 member B

Khoo, H. E., Azlan, A., Tang, S. T. & Lim, S. M. Anthocyanidins and anthocyanins: colored pigments as…
#NewsBeep #News #Headlines #Anthocyanidin #Cellbiology #Chemicalbiology #Fam222B #Geneticscreening #HumanitiesandSocialSciences #Latvia #LV #MicroRNA #multidisciplinary #Science
https://www.newsbeep.com/53145/

Cytology and GeneticsJul 31
Creation and Application of Liposomal Form of MicroRNA for the Treatment of Neurodenegratative Diseases - #nondegenerativediseases #Alzheimer’sdisease #therapeuticagents #microRNA #delivery #liposomes #genetics - https://link.springer.com/article/10.3103/S0095452725020094
Creation and Application of Liposomal Form of MicroRNA for the Treatment of Neurodenegratative Diseases - Cytology and Genetics

Abstract Targeted delivery of active pharmaceutical ingredients, such as microRNAs, is a pressing issue. The use of liposomes as targeted carriers of various therapeutic agents has certain advantages and is currently growing significantly. Liposomes are capable of transporting both hydrophilic and hydrophobic molecules simultaneously. Liposomes have relatively high stability under physiological conditions and controlled release of encapsulated ingredients, and are biocompatible with cell membranes. Liposome-encapsulated microRNA-based drugs may become a certain alternative to classical therapeutic agents in the treatment of neurodegenerative diseases. Neuroinflammation is known to be mediated through complex interactions between cells of the central nervous system (CNS) and the periphery. Although the inflammatory response in the healthy brain is tightly controlled by numerous regulatory mechanisms, deregulation can occur in these processes under pathological conditions. Such deregulation leads to uncontrolled neuroinflammation. Among the main regulators of these processes, microRNAs play an important role. Due to miRNAs, processes can become deregulated, contributing to disease progression, or may reflect a homeostatic attempt by the CNS to prevent excessive damage and restore normal functioning conditions. The paper summarizes the literature data on the creation, properties, and application of the liposomal form of miRNA, in particular msiRNA-101, in the development of Alzheimer’s disease.

SpringerLink
JapanJun 22

Japanese startup’s urine-based cancer test shows early detection potential | Health

A URINE-based cancer screening kit developed by Japanese startup Craif Inc. has demonstrated encouraging results in detecting early-stage cancer non-i…
#Japan #JP #JapanNews #craifinc #earlycancerdetection #healthcaretech #Hokkaido #Japanese #Japanesenews #medicalinnovation #microrna #misignal #news
https://www.alojapan.com/1304419/japanese-startups-urine-based-cancer-test-shows-early-detection-potential-health/

Alo JapanJun 22
https://www.alojapan.com/1304419/japanese-startups-urine-based-cancer-test-shows-early-detection-potential-health/ Japanese startup’s urine-based cancer test shows early detection potential | Health #CraifInc #EarlyCancerDetection #HealthcareTech #Hokkaido #Japan #JapanNews #Japanese #JapaneseNews #MedicalInnovation #microrna #misignal #news A URINE-based cancer screening kit developed by Japanese startup Craif Inc. has demonstrated encouraging results in detecting early-stage cancer non-invasively, according to a report by Kyodo News. Craif Inc., a spin- …
HusnainJun 11

🚨 Our Frontiers in Molecular Neuroscience review explores how microRNAs (miRNAs) could transform early diagnosis of neurodegenerative diseases 🧠

🧬 Also covers aging & protein PTMs!
📖 https://doi.org/10.3389/fnmol.2024.1386735
#Neuroscience #microRNA #Neurodegeneration #Biomarkers #Alzheimers #OpenScience

HusnainApr 20

🧠 Exciting News! Our review article is published!
We explore how miRNAs could enhance diagnostics and their role in PTM and Aging 🧠🧬
🔗https://doi.org/10.3389/fnmol.2024.1386735
🔗 https://go.nature.com/3FSQrke

#MicroRNA #Neurodegeneration #PostTranslationalModifications #AgingAndDisease #MolecularNeuroscience #RNARegulation #GeneExpression #Biomarkers #EarlyDiagnosis #FrontiersInNeuroscience #ScientificResearch #BTU #Charite #DZNE #BrainHealth #Epigenetics #NextGenDiagnostics #Neurobiology #miRNABasedDiagnostics

Frontiers | MicroRNA biomarkers as next-generation diagnostic tools for neurodegenerative diseases: a comprehensive review

Neurodegenerative diseases (ND) are characterized by abnormalities within neurons of the brain or spinal cord that gradually lose function, eventually leadin...

Frontiers
John Vaccaro (johniac)Feb 28

SciTech Chronicles. . . . . . . . .Feb 28, 2025

https://bit.ly/stc022825

#corn #earworm #flavonoids #microbiome ##Quantum-computing #linking #connectivity #12-qubit ##Vesuvius #brain #X-rays #vitrification #microbes #modules #free-living #ecosystem #bamboo #microRNA #feeding #regulators

SciTech Chronicles. . . . . . . . .Feb 28th, 2025

Some make amends... Some make a wound. Vol II No 53 315 links Curated flavonoidcompounds have an insecticidal effect on corn earworm larvae....

Cytology and GeneticsJan 28
A Comprehensive Review on Liver Regeneration Termination: A Non-Neglectable Phase - #liverregenerationtermination #cellinvolvement #cytokines #signalingpathways #gutmicrobiota #microRNA #liverregeneration #liver - https://link.springer.com/article/10.3103/S0095452724040030
A Comprehensive Review on Liver Regeneration Termination: A Non-Neglectable Phase - Cytology and Genetics

Abstract As the most important organ of detoxification in the body, the liver also has the strong regenerative ability itself. The liver can regenerate after partial hepatectomy (PH) and completely restore to its original mass. Liver regeneration (LR) has become one of research hotspots in the field of regenerative biology. Previous basic studies have predominantly concentrated on the initial and proliferative phases of regenerative response, while a relatively little attention has been paid to the mechanism of proper termination of liver regeneration. In recent years, along with the increasing recognition of the significance of LR termination, the growing researches have been carried out and some achievement has been made in a certain extent. The successful completion of LR is considered to involve many cells, growth factors, signaling pathways, metabolites and other extrahepatic factors. This article will review the progression of research on the mechanism of LR termination after PH in recent years.

SpringerLink