Excessive #alcoholconsumption reduces the body’s ability to fight off #infections and may make people more susceptible to #pneumonia and other #respiratory problems. This does not mean that all amounts of alcohol immediately suppresses #immunity. Research shows that #moderate consumption of #phenolrich #wine or #beer, a maximum of 12 grams for women and 24 grams for men, can be #beneficial to #immunesystemfunction by triggering #humoral #immuneresponses. #angstromminerals #healthychoices

🧬💡 mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the #immunesystem📚
A study by researchers from the #UniCologne and the University Clinic Cologne shows that mRNA vaccines against COVID-19 not only trigger classical #immuneresponses, but also have a persistent effect on the innate immune system. These changes may enable the human body to respond faster and more broadly to future #infections. 🦠

Learn more ➡️ https://uni.koeln/43N7Y

#UniKöln #Uniklinikkoeln #mRNA #Vaccine #COVID

mRNA-Coronaimpfung trainiert das „Langzeitgedächtnis“ des Immunsystems

Forschende der Universität zu Köln zeigen, dass COVID-19-Impfstoffe auf der Grundlage von mRNA das angeborene Immunsystem langfristig prägen. Diese Mechanismen können bewirken, dass der menschliche Körper auf künftige Infektionen schneller und breiter reagieren kann / Veröffentlichung in „Molecular Systems Biology“

Moderna combi flu and Covid jab gives better protection, study finds

Clinical trials show two-in-one jab may bring about higher immune responses than separate inoculations

The Guardian
When the immune system attacks the immune system: #Autoantibodies against #interferons (type I) have an impact on #immuneresponses and are associated with viral disease susceptibility as outlined in this elegant review... #immunology #virology #cytokines #infections #autoimmunity #immunoregulation
https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202250164
New insights in #pancreaticcancer and #immuneresponses upcoming at the CIMT meeting: metabolic regulation and immune control under pressure from #chemotherapy ... #translationalmedicine at work http://www.meeting.cimt.eu/ #immunology
CIMT-Meeting

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection
#Vaccines
#VaccinesWork
#Covid
#SARSCov2
#BreakthroughInfection
#ImmuneResponses https://www.news-medical.net/news/20230209/Prior-vaccination-enhances-immune-responses-during-SARS-CoV-2-breakthrough-infection.aspx
>Researchers assess the impact of COVID-19 vaccination on immune responses during a breakthrough infection.
Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Researchers assess the impact of COVID-19 vaccination on immune responses during a breakthrough infection.

News-Medical.net
@MHCaDreamer Absolutely relevant topic! There are so many questions in this field, especially around the possible secondary problems with #cellulartherapies and #CARTs ...also in light of the different #immuneresponses and immune regulations in different #cancer entities...hem vs. solid tumors etc. #immunology #Immunotherapy
@mvdb @schumacher Way to go: include the full set of immune cell subpopulations... #organoids #tme #immunology #immuneresponses
https://www.pnas.org/doi/10.1073/pnas.2209856120
Tertiary lymphoid structures in the microenvironment might indicate not only beneficial #Immunotherapy #immuneresponses but also point to immune-related side effects. #oncology #Immunology #ImmuneSystem https://insight.jci.org/articles/view/165108
JCI Insight - Tertiary lymphoid structure signatures are associated with immune checkpoint inhibitor related acute interstitial nephritis

Should we assess chromosome 9p deletions before giving #immunotherapy to patients with solid #tumors ? Tantalizing data on interferon in #immuneresponses from Scott Lowe published here... https://www.nature.com/articles/s43018-022-00443-5
MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis - Nature Cancer

Barriga et al. develop MACHETE, a genome engineering strategy enabling the flexible modeling of megabase-sized deletions and show that the concomitant loss of the interferon cluster with CDKN2A/B deletions on 9p21.3 enhances immune evasion.

Nature