Maries van den Broek

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Immunology professor and vice-dean for research at the University of Zurich, mother, theater-lover and rowing-addict.
URLhttps://www.immunology.uzh.ch/en/researchunit/oncology.html
We can’t sufficiently emphasize the importance of fundamental science: https://www.nature.com/articles/d41586-022-04172-8.pdf

How to stop Killers from turning on each other?

Engineering CAR-NK cells with ‘don’t kill me’ ligands circumvents problem of trogocytosis-mediated fratricide.

https://www.nature.com/articles/s41591-022-02003-x

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape - Nature Medicine

A new dual-chimeric antigen receptor (CAR) system enhances the antitumor activity of CAR natural killer cells and makes them less susceptible to therapeutic resistance in preclinical models.

Nature
To all immunologists who don‘t yet know: Check out this great seriers of online talks (also available on demand) - Global ImmunoTalks: https://labs.biology.ucsd.edu/zuniga/global_immunotalks.htm
Zuniga Lab | Division of Biological Sciences

Any questions about MHC molecules? Check out this link: https://ccb.lumc.nl/comic-book-273
Comic book - Cell & Chemical Biology

I‘d love to connect with (tumor-)immunologists.