The article examines whether psychedelic therapy and traditional antidepressants yield similar improvements in depression when both are studied under open-label conditions, suggesting that study design and expectations may account for some previously observed advantages of psychedelics. It also discusses methodological issues like functional unblinding and the implications for interpreting treatment effectiveness.

This topic is of interest to psychology readers because it highlights how study design, expectations, and placebo-related factors can influence observed treatment outcomes, underscoring the complexity of evaluating novel therapies within mental health research.

Article Title: Psychedelic therapy and traditional antidepressants show similar results under open-label conditions

Link to PsyPost Article: https://www.psypost dot org/psychedelic-therapy-and-traditional-antidepressants-show-similar-results-under-open-label-conditions/

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#psychedelictherapy #depressionresearch #clinicaltrials #openlabel #blindingissues

Clinical trial: Evaluation of the Effects of Laughter Yoga on Pain Intensity, Stress, and Beta-endorphin Levels in Patients With Multiple Sclerosis

https://clinicaltrials.gov/study/NCT07524231?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20406

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Comparison of Frailty, Physical Fitness Parameters, and Irisin Levels Between Patients With Multiple Sclerosis and Healthy Volunteers

https://clinicaltrials.gov/study/NCT07521982?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20407

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: An Open-Label Clinical Study to Evaluate the Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases.

https://clinicaltrials.gov/study/NCT07526493?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20408

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Influance of Walking Fatigability on Spatiotemporal Gait Parameters and Risk of Falling in Patients With Multiple Scalerosis

https://clinicaltrials.gov/study/NCT07524556?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20409

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: A Clinical Study on the Safety and Tolerability of Universal STAR-T Cell Injection in Patients With Multiple Sclerosis.

https://clinicaltrials.gov/study/NCT07523100?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20410

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: The Effect of an Exercise Intervention on Serum Glial Fibrillary Acidic Protein (GFAP), Brain Volumetry and and Functional Outcomes in Patients With Multiple Sclerosis: A Randomized Controlled Trial

https://clinicaltrials.gov/study/NCT07521995?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20411

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

F.D.A. Calls on Drug Developers to Publish Missing Data from Thousands of Trials

https://fed.brid.gy/r/https://www.nytimes.com/2026/04/13/well/fda-clinical-trials.html

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