Leveraging intratumoral probiotics for pancreatic cancer #immunotherapy via xenophagy.
#probiotic #microbiology #immunology
https://www.cell.com/cell-host-microbe/abstract/S1931-3128(26)00078-8
Leveraging intratumoral probiotics for pancreatic cancer #immunotherapy via xenophagy.
#probiotic #microbiology #immunology
https://www.cell.com/cell-host-microbe/abstract/S1931-3128(26)00078-8
Catch-bond interactions are not easy to grasp compared to affinity and specificity. How are they measured, and is the approach reproducible?
🎯 HCC treatment is evolving…
TACE + immunotherapy + targeted therapy shows stronger outcomes—but are we ready to change practice?
⚠️ Promising data, but guidelines still need phase III confirmation
#GastroAGI #HCC #LiverCancer #TACE #Immunotherapy #TargetedTherapy #Hepatology #Oncology #MedEd
@xs4me2 Wetenschappers laten deze week zien dat de gezondheid van dit orgaan, ook wel thymus genoemd, verband houdt met levensduur, veroudering, risico op hart- en vaatziekten en kanker
Echte ontdekkings wetenschap waarbij #ai nuttig is ingezet bij een deel van de studie
#kanker #Immunotherapy
MIIP Protein Blocks Colorectal Cancer Via Control of Immune Response
https://orbitnewshub.com/miip-protein-blocks-colorectal-cancer-via-control-of-immune-response/
#ColorectalCancer #MedicalResearch #Immunotherapy #OrbitNewsHub #HealthNews #CancerResearch
New publication on the role of #macrophages in shaping the tumor #microenvironment in #cancer ... leading to the exploration of #adipose tissue and it's impact on #innateimmunity and #adaptiveimmunity in #ovariancancer to the point where resistancr to #immunotherapy is observed. These findings are then put into action for patient stratification, showing the utility in #radiology and #medicaloncology and #oncology #Science #medicine #immunology

0 likes, 0 comments - drhowardsmithreports on March 10, 2026: "Laser-Aided Immunotherapy For Brain Cancer Adding a laser procedure dramatically improves the results of immunotherapy for one of the deadliest brain cancers. Neuro-oncologists at USC report this development in the journal Nature Communications. In this Phase 1/2 clinical trial, 45 patients with recurrent astrocytoma were randomized to receive either laser interstitial thermal therapy (LITT) that destroys tumor tissue and opens the blood-brain barrier plus the immunotherapy with the drug pembrolizumab immunotherapy or standard care, surgery, followed by the immunotherapy. The results are striking: nearly 50% of patients in the LITT group were alive at 18 months, compared with 0% in the standard-treatment group. In addition, more than one-third of LITT-treated patients survived beyond three years, compared to a typical 4–5 month survival seen with surgery and immunotherapy. The addition of of LITT, adding laser therapy to immunotherapy, is a potential game-changing approach. These results are early and require confirmation in larger trials, they offer real hope in a disease with limited therapeutic options and generally poor outcomes. https://doi.org/10.1038/s41467-026-69522-w https://www.news-medical.net/news/20260226/Innovative-laser-procedure-offers-new-hope-for-recurrent-brain-tumors.aspx #laser #immunotherapy #astrocytoma #cancer".
🦠 Melanoma - Feb 2026
• Personalized mRNA vaccine shows durable reduction in melanoma recurrence
• HOXD13 regulates angiogenesis and immune evasion in melanoma
• Pepyrus boosts sensitivity in HLA-bound neoantigen discovery
• SITC defines consensus criteria for ICI resistance
• Vibostolimab adds no benefit over pembrolizumab alone in melanoma
• Pathologic response assessment shows high reproducibility across tumor types