Mastodawn

Systemic candidiasis is a severe, opportunistic #fungal infection caused by Candida albicans. Recent research demonstrates that reprogramming the metabolic pathways of a host's immune cells offers a viable strategy to clear the infection, circumventing the need for traditional #antifungal medications.
#Immunology #Microbiology #sflorg
https://www.sflorg.com/2026/04/imgy04032601.html

Study Points Toward Immune Reprogramming to Treat Candidiasis

Systemic candidiasis is an opportunistic fungal infection that has been difficult to treat effectively

David Ojcius 2h ago

Lactic acid drives #NLRP3 #inflammasome activation and caspase-1–like cytokine cleavage via intracellular acidification

https://www.nature.com/articles/s41419-026-08708-y #OpenAccess #immunology

David Ojcius 2h ago

High-fat #diet causes rapid loss of intestinal group 3 innate lymphoid cells through #microbiota-driven inflammation & mitochondrial stress.

Dietary fats and microbes trigger ILC3 metabolic failure & death, disrupting intestinal homeostasis.

#immunology #microbiology

https://davidojcius.blogspot.com/2026/04/high-fat-diet-causes-rapid-loss-of.html

David Ojcius 3h ago

Acute and chronic infections drive distinct trajectories in human memory CD4+ T cell formation.

CD4⁺ T cell fates in #HCV differ by outcome, revealing distinct chronic, cleared, and cured memory paths.

https://www.sciencedirect.com/science/article/pii/S1074761326001196 #hepatitis #immunology #microbiology #virology

Scientific Frontline 1d ago

Infants diagnosed with food protein-induced enterocolitis syndrome (FPIES) exhibit a distinctly altered and atypical gut bacterial composition compared to healthy individuals, marking a clear biological association with the rare allergic disease.
#Immunology #Microbiology #Pediatrics #Gastroenterology #sflorg
https://www.sflorg.com/2026/04/imgy04022601.html

Gut microbiota differs in children with rare food allergy

FPIES (food protein-induced enterocolitis syndrome) is a form of food allergy in which the body reacts without the usual allergy antibodies

TKSST • seethis.tv 🌈🪐✨1d ago

🧬🐍 Researchers have developed a breakthrough antivenom cocktail using antibodies from Tim Friede, who spent two decades building immunity through controlled exposure to lethal snake bites.

👉 https://www.popularmechanics.com/science/animals/a70910190/snake-man-antivenom_1775069861/

#biology #medicine #snakes #science #immunology #research #wildlife #herpetology #health #research

The Man Who Let Deadly Snakes Bite Him for 20 Years—And the Universal Antivenom Hiding in His Blood

The antivenom could provide unprecedented protection against some of the world’s deadliest snakes.

Popular Mechanics

kaffando 1d ago

I'm looking for an #Immunologist who might have an interest in unusual presentations. Someone with a curious mind, shall we say.

If such a person exists in #mastodon it would be great to connect with them.

All boosts gratefully received!

#Immunology

MrMed : Online Pharmacy 3d ago

Discover the essential strategies doctors use to ensure transplant success, from HLA matching to the latest in immunosuppressant therapy and lifestyle management.
https://hasster.com/blogs/348912/5-Key-Factors-That-Prevent-Organ-Transplant-Rejection

#OrganTransplant #TransplantWarrior #MedicalScience #Immunology #DonateLife #HealthTech #TransplantSuccess

David Ojcius 6d ago

Glibenclamide attenuates neuronal #pyroptosis by modulating KATP channels in the hippocampus of palmitic acid-induced lipotoxic mice

https://www.sciencedirect.com/science/article/pii/S2319417026000284 #OpenAccess #inflammasome #inflammation #immunology

David Usharauli Mar 27

Interesting, but the abstract fails to link gut Th17 cells to subcutaneous self-antigen immunization. It would have been simpler to state that immunization expands pre-existing gut-derived Th17 cells that contribute to neural inflammation.

#immunology

https://www.science.org/doi/10.1126/sciimmunol.aec1627