physician-scientist, immunologist, oncologist, developer of novel therapies, computer nerd, principal investigator,...[my own views only]
https://www.dkfz.de/en/translationale-immuntherapie/index.php
No license, implied or explicit, is granted to use any of my posts for machine-learning/AI/LLM development or training.
New co-author paper time!
"Discovery and Dynamics of a Sedna-like object with a perihelion of 66 au"
(Full disclosure, I'm author number 20 out of 33 authors, and only had a teeny tiny minor part in this discovery, but I'm still excited about it)
Motivation: Many transcriptome creation workflows are not standardized, are difficult to install or share, prone to breaking as dependencies update or cease to be maintained and are resource intensive. Due to a lack of authoritative literature, many also overlook potentially important steps, such as thinning contig over-assembly or identifying transcript consensus across samples, which reduce resource demands during annotation and increase the accuracy of final transcripts. Results: We developed TATAT, a modular, Dockerized software that contains all the tools necessary to generate an annotated coding transcriptome from raw RNA-seq data. The tools remain in a static state and can be coordinated with bash and python scripts provided therein, making TATAT a standardized, reproducible workflow that can easily be shared and installed. We preferentially incorporate tools that are not only accurate, but are fast and require less RAM, and subsequently show TATAT can generate a comprehensive transcriptome for a non-model organism, the Egyptian rousette bat (Rousettus aegyptiacus), in ~8 hours in a high-performance computing (HPC) environment. Availability and implementation: The TATAT code, instructions, and tutorial are available at https://github.com/viralemergence/tatat. ### Competing Interest Statement The authors have declared no competing interest. National Science Foundation, https://ror.org/021nxhr62, 2515340
Bliss
Milford Sound, NZ
Such an amazing location and I got lucky with the light and atmosphere.
#newzealand #landscape #LandscapePhotography #nature #naturephotography #mountains #PhotoMonday #FotoMontag #photo #photography #noai #AntonGorlinPhotos
This interstellar comet may be a frozen relic from before the Sun
A newly discovered comet, 3I/ATLAS, may be the most ancient visitor ever detected, potentially older than our solar system itself. Unlike previous interstellar objects, this ice-rich comet seems to originate from the thick disk of the Milky Way, a region filled with ancient stars. First spotted in July 2025, it’s already showing signs of activity and could help https://www.sciencedaily.com/releases/2025/07/250711082920.htm
A newly discovered comet, 3I/ATLAS, may be the most ancient visitor ever detected, potentially older than our solar system itself. Unlike previous interstellar objects, this ice-rich comet seems to originate from the thick disk of the Milky Way, a region filled with ancient stars. First spotted in July 2025, it’s already showing signs of activity and could help scientists understand more about galactic chemistry and the origins of planetary systems.
dillyd
Prof. Sam Lawler
Anja
bioRxiv
Anton Gorlin
Martti Lamppu 🇫🇮🇪🇺🇺🇦
Science Scholar