Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
https://onlinelibrary.wiley.com/doi/10.1002/ange.202517243
#Chemistry #ChemBio #Covalent #CovalentInhibitor







