New preprint! Which segmentation algorithm should you use for image-based spatial transcriptomics — and does the answer change by tissue?

Preprint: https://www.biorxiv.org/content/10.64898/2026.04.16.718947v1

#SpatialBiology #Bioinformatics #computationalbiology #OpenScience

🧩 Could RNA and proteins share the same “shape language” for binding drugs?

🔗 Eigenvalue Ratios Reveal Shared Binding Pocket Shapes in RNA and Protein Structures. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0022

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #StructuralBiology #ComputationalBiology #RNAResearch #ProteinScience #Bioinformatics #MolecularModeling #Genomics #Proteomics #Cheminformatics #LigandBinding

Job Alert

PhD position in Computational Phylogenetics (100%)

Location: Wädenswil
Deadline: open until filled

https://www.academiceurope.com/ads/phd-position-in-computational-phylogenetics-100/

#hiring #ComputationalBiology #Phylogenetics #MachineLearning #Bioinformatics #Genomics #PhD #AIinScience

Hey, gonna try my luck here with something technical:

Anyone has or knows of software or have public code to randomly select SNPs from a population or vcf file based on properties which as MAF, distance to TSS of nearest genes?

I can write something, but I'm hoping to save time here and can't find anything. I need it to do an enrichment analysis where I test real hits from the SNPs vs hits from the random ones.

#genomics #bioinformatics #gwas #academia #science #computationalbiology

Biologists MUST learn AI now! Drug discovery accelerating, genomics exploding with massive datasets 🧬💻
Bioinformatics + AI skills = scientists in HIGH demand. Don't get left behind! 🚀
Join BioResire WhatsApp for AI-Bio training 👇 https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#AIBiology #Bioinformatics #BiotechAI #Genomics #DrugDiscovery #BioinformaticsTraining #LifeScienceAI #AIinBiology #BiotechCareers #BioinformaticsJobs #ResearchAI #GenomicsData #ComputationalBiology #BiotechFuture #LifeSciences

📊 Bioinformatics - Mar 2026

• CellVoyager AI agent autonomously analyzes scRNA-seq data
• Structural variants drive 60%+ of pediatric cancer mutations
• ANNEVO improves gene annotation across diverse genomes
• Sildenafil identified as potential therapy for Leigh syndrome

https://pir.sh/z0odQ2baLO

#Bioinformatics #ComputationalBiology

Microbiome Bioinformatician (Postdoc) - Metagenomics and Metaproteomics
Charité Universitätsmedizin Berlin

Come join us a #bioinformatics / #computationalbiology postdoc to explore the #microbiome using #metaproteomics and #metagenomics

See the full job description on jobRxiv: https://jobrxiv.org/job/charite-universitatsmedizin-berlin-27778-mic...
https://jobrxiv.org/job/charite-universitatsmedizin-berlin-27778-microbiome-bioinformatician-postdoc-metagenomics-and-metaproteomics/?fsp_sid=11065

Microbiome Bioinformatician (Postdoc) - Metagenomics and Metaproteomics
Charité Universitätsmedizin Berlin

Come join us a #bioinformatics / #computationalbiology postdoc to explore the #microbiome using #metaproteomics and #metagenomics

See the full job description on jobRxiv: https://jobrxiv.org/job/charite-universitatsmedizin-berlin-27778-mic...
https://jobrxiv.org/job/charite-universitatsmedizin-berlin-27778-microbiome-bioinformatician-postdoc-metagenomics-and-metaproteomics/?fsp_sid=11033

🎤 It is a pleasure to welcome Stephen Quake, from Stanford University as a keynote speaker at ECCB 2026! A pioneer in bioengineering and genomics, he has developed groundbreaking technologies in DNA sequencing, microfluidics, & non-invasive diagnostics that have transformed both research and clinical practice.

👉 Interested in attending? Register by 14 August: https://eccb2026.org/registration-information
📍 Geneva

Stanford University School of Medicine
#ECCB2026 #computationalbiology #bioinformatics #GenevaLovesData