🦠 Could algorithms help us outpace evolving superbugs?

πŸ”— Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008

πŸ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AntibioticResistance #DrugDiscovery #ComputationalBiology #StructuralBiology #MachineLearning #Bioinformatics

🧱 What if activation and inhibition are not about binding but about motion?

πŸ”— Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017

πŸ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines

🀯 What if most β€œbiological insights” are just mixed-up signals we never untangled?

πŸ”— Integrative Learning of Disentangled Representations from Single-Cell RNA-Sequencing Datasets. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0015

πŸ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SystemsBiology #Genomics #Bioinformatics #ComputationalBiology #AIinBiology #SingleCell #MachineLearning #DataScience #LifeSciences

🧬 Can we map the cascade of gene activity that guides cells through differentiation?

πŸ”— Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis. Computational and Structural Biotechnology Journal (CSBJ). https://spj.science.org/doi/epdf/10.34133/csbj.0007

πŸ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SingleCell #Genomics #Bioinformatics #SystemsBiology #GeneExpression #ComputationalBiology

🧬 Bioinformatics - Feb 2026

β€’ Microbial dispersal and gene flow identified as key drivers of microbiome structure
β€’ 22-protein panel distinguishes multiple sclerosis from other inflammatory diseases
β€’ LUMI-lab autonomously synthesized 1,700+ lipid nanoparticles for mRNA delivery
β€’ 134 mutational signatures identified across 16 cancer types
β€’ Improved polygenic risk scores for breast cancer in African-ancestry women

https://pir.sh/pzy1b5yglv

#Bioinformatics #ComputationalBiology #Genomics

Bioinformatics Research Summary February 2026 - Summarized Science

Summary of key Bioinformatics publications highlighting major findings, clinical relevance, and emerging research trends.

πŸŽ‰ Registration for ECCB 2026 is now open!
We are excited to welcome the European #ComputationalBiology & #Bioinformatics community to Geneva (31 Aug–4 Sept 2026).

Organized by SIB, #ECCB2026 will bring together researchers from around the world for five days of science, collaboration, and inspiration.

πŸ‘‰ More info: https://eccb2026.org/registration-information

⏰ Early bird until 31 March

Current open calls :
πŸ”Ή Proceedings papers until 16 March
πŸ”Ή Highlight talks & posters until 20 April

#GenevaLovesData

Protected learning is a biological mechanism in which adult animals create staged, risk-mitigated developmental spaces, allowing offspring to safely acquire essential survival skills without facing immediate lethal consequences.
#ComputationalBiology #TheoreticalBiology #Ethology #EvolutionaryBiology #sflorg
https://www.sflorg.com/2026/03/bs03022601.html
Survival training in a safe space

To improve their chances of survival, animals must learn – and that can be dangerous.

New AI methods let scientists merge RNA‑seq, imaging and other data, revealing hidden cellular states. This multimodal approach could accelerate discoveries in cell biology and computational biology. Learn how machine learning bridges data integration across experiments. #MultimodalAI #CellBiology #RNAseq #ComputationalBiology

πŸ”— https://aidailypost.com/news/ai-enables-scientists-integrate-multiple-cell-measurements