Safety Warning for people on Rapamycin / Sirolimus / Rapamune

Chrysanthemum, Dandelion, Bishop's Weed, and/or Liquoirce, even if blended with other tea ingredients, can interact with the medications, including stopping absorption & be potentially dangerous. Please be careful.

For me personally, chrysanthemum tea blocked the efficacy of my latest dose of rapamycin. I'm really hoping that's all that it did.

https://pubmed.ncbi.nlm.nih.gov/24824478/

#LongCovid #MECFS #rapamycin #sirolimus #transplant #polybio #putrinoLab #rapamune #mTorInhibitor #lymphaticMalformation #TuberousSclerosisComplex

🗿 A billion-dollar drug was found in Easter Island soil: What companies owe the Indigenous people they studied

https://theconversation.com/a-billion-dollar-drug-was-found-in-easter-island-soil-what-scientists-and-companies-owe-the-indigenous-people-they-studied-250586

#easterisland #drugs #pharmacology #indigenous #globalsouth #rapamycin

Rapamycin: Mouse Miracle, Human Mystery - Rhonda Patrick and Peter Attia MD

#rapamycin #longevity

#Indigenous #RapaNui #antibiotics #rapamycin

"An antibiotic discovered on Easter Island in 1964 sparked a billion-dollar pharmaceutical success story. Yet the history told about this “miracle drug” has completely left out the people and politics that made its discovery possible.

Named after the island’s Indigenous name, Rapa Nui, the drug rapamycin was initially developed as an immunosuppressant to prevent organ transplant rejection and to improve the efficacy of stents to treat coronary artery disease. Its use has since expanded to treat various types of cancer, and researchers are currently exploring its potential to treat diabetes, neurodegenerative diseases and even aging. Indeed, studies raising rapamycin’s promise to extend lifespan or combat age-related diseases seem to be published almost daily. A PubMed search reveals over 59,000 journal articles that mention rapamycin, making it one of the most talked-about drugs in medicine.

Despite being so ubiquitous in science and medicine, how rapamycin was discovered has remained largely unknown to the public. Many in the field are aware that scientists from the pharmaceutical company Ayerst Research Laboratories isolated the molecule from a soil sample containing the bacterium Streptomyces hydroscopicus in the mid-1970s. What is less well known is that this soil sample was collected as part of a Canadian-led mission to Rapa Nui in 1964, called the Medical Expedition to Easter Island, or METEI.

As a scientist who built my career around the effects of rapamycin on cells, I felt compelled to understand and share the human story underlying its origin. Learning about historian Jacalyn Duffin’s work on METEI completely changed how I and many of my colleagues view our own field.

Unearthing rapamycin’s complex legacy raises important questions about systemic bias in biomedical research and what pharmaceutical companies owe to the Indigenous lands from which they mine their blockbuster discoveries."

https://theconversation.com/a-billion-dollar-drug-was-found-in-easter-island-soil-what-scientists-and-companies-owe-the-indigenous-people-they-studied-250586

A billion-dollar drug was discovered in soil samples from Easter Island decades ago, but the question remains — what do scientists and pharmaceutical companies owe the Indigenous Rapa Nui people whose land and knowledge were drawn upon?
This case highlights the urgent need for fair benefit sharing, ethical research practices, and genuine respect for Indigenous sovereignty when global industries profit from local resources.

#indigenousrights #scienceethics #bioprospecting #rapanui #rapamycin #multinationals #bigpharma

https://theconversation.com/a-billion-dollar-drug-was-found-in-easter-island-soil-what-scientists-and-companies-owe-the-indigenous-people-they-studied-250586

https://medicalxpress.com/news/2025-09-rapamycin-linked-dna-resilience-aging.html

(boomer bolstering )

Originally developed for organ transplantation to prevent immune rejection, previous research has found that, at non-#immunosuppressive doses, #rapamycin can mitigate cellular #senescence.

"rapamycin provides direct #genomicprotection in human immune cells and may support healthy aging, offer benefits after clinical #radiationexposure, and could even address risks from #cosmicradiation during extended #spacetravel."