I teach medical students that autophagy -- the body's cellular "recycling system" -- is one of the most powerful anti-aging mechanisms we have. Until now, we had no direct human proof that fasting triggers it.

That just changed.

Cedars-Sinai researchers ran the first human trial measuring autophagic flux during a 5-day fasting-mimicking diet. Results:

- Measurable increase in cellular recycling (autophagy f... https://pubmed.ncbi.nlm.nih.gov/41372565/

#Autophagy #Fasting #MetabolicHealth #Longevity #AntiAging

As a medical school professor, I teach students that vitamin D does far more than build bones. This new study shows just how much more.

Researchers found that vitamin D supplementation significantly improved glucose tolerance, lowered fasting blood sugar, and reduced insulin resistance in diabetic mice. But the real discovery was the mechanism.

Vitamin D activated autophagy, the body's cellular cleanup sy...
#VitaminD #Autophagy #Inflammation #MetabolicHealth #Diabetes

https://pmc.ncbi.nlm.nih.gov/articles/PMC12962641/

#OnThisDay The #DavisCup competition, premier international team event in men's tennis, was established (1900)

Happy Birthday Australian #Cricketer Glenn McGrath (1970) - considered one of the greatest bowlers in cricketing history.

Happy Birthday Yoshinori Ohsumi (1945). He discovered of mechanisms for #Autophagy - the process that cells use to destroy and recycle cellular components and received the 2016 Nobel Prize in Physiology or Medicine for his discovery.

https://knowledgezone.co.in/news

#Genetics #Genomics #Academia #AcademicChatter

Technology is bonkers. We've got an #autophagy project that's been going on, oh I don't know, maybe 2.5 years at this point. Or three? Maybe three years. Quite a bit of RNA-Seq involved with three conditions in primary cells.

I just did some quick tallying. 45 samples. About 2.08 billion reads.

2009 me would be flabbergasted at the amount of sequencing. Now it's just how things are.