Stop late-night snacking! 🚫🍔 The 3-Hour Rule activates Autophagy and lets Sirtuins repair your DNA. Become biologically younger overnight. All the facts from the Northwestern University study in the video. #Autophagy #Longevity #HealthyAging #Biohacking

https://www.youtube.com/watch?v=C81IqIxnaWM&list=PLCFAL8lW1qRc2_ByG_7s4bc6h4hcK19_b&index=1

#OnThisDay The #DavisCup competition, premier international team event in men's tennis, was established (1900)

Happy Birthday Australian #Cricketer Glenn McGrath (1970) - considered one of the greatest bowlers in cricketing history.

Happy Birthday Yoshinori Ohsumi (1945). He discovered of mechanisms for #Autophagy - the process that cells use to destroy and recycle cellular components and received the 2016 Nobel Prize in Physiology or Medicine for his discovery.

https://knowledgezone.co.in/news

#Genetics #Genomics #Academia #AcademicChatter

Technology is bonkers. We've got an #autophagy project that's been going on, oh I don't know, maybe 2.5 years at this point. Or three? Maybe three years. Quite a bit of RNA-Seq involved with three conditions in primary cells.

I just did some quick tallying. 45 samples. About 2.08 billion reads.

2009 me would be flabbergasted at the amount of sequencing. Now it's just how things are.

`..phosphorylation of Optineurin by TBK1 induces the formation of filaments that phase separate upon binding to linear polyubiquitin.. the condensation of filamentous Optineurin with ubiquitylated cargo promotes the nucleation of cargo and its subsequent alignment with LC3-positive nascent autophagosomes, suggesting that co-condensation processes ensure directionality in selective autophagy`

https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509927

#autophagy #optineurin #condensates