Cellular
#senescence is a biological paradigm in which a unique subpopulation of cells permanently and irreversibly stops dividing but evades apoptosis (programmed cell death). Instead of dying off, these arrested "zombie cells" remain metabolically hyperactive and linger within mammalian tissues.
#WhatIs #MolecularBiology #CellBiology #Geroscience #Longevity #sflorghttps://www.sflorg.com/2026/03/wi03202601.html
What Is: Cellular Senescence
Cellular senescence is recognized as a fundamental driver of "inflammaging"—chronic, systemic inflammation associated with advanced age.
The key to the cure for aging may lie in extracellular vesicles
Senescence. It’s a beautiful-sounding word whose tones suggest it should be a perfume or an essential oil. But that’s not even close. Senescence is the loss of a cell’s power to divide and grow, thus causing deterioration. It’s aging, completely unavoidable, and a 100% guaranteed pathway to death.
A grad student’s wild idea triggers a major aging breakthrough
Senescent “zombie” cells are linked to aging and multiple diseases, but spotting them in living tissue has been notoriously difficult. Researchers at Mayo Clinic have now taken an inventive leap by using aptamers—tiny, shape-shifting DNA molecules—to selectively tag these elusive cells. The project began as an offbeat conversation between two graduate students and quickly evolved into a collaborative, cross-lab effort that uncovered aptamers capable of binding to unique surface proteins on senescent cells.
my reading for this evening -
Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/
#aging #senescence #GutMicrobiome #pathoadaptation
Aging: a possible road toward gut microbiota pathoadaptation - PubMed
Laboratory-raised mice live approximately seven times longer and healthier lives compared to their wild counterparts, due to a standardized healthy diet and limited exposure to environmental stressors. Aging is associated with increased inflammation and microbial dysbiosis. Collectively, these influ …
Pink Flamingos Reveal Their Secret To Aging
"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."
#SciComm by @grrlscientist
#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667
Pink Flamingos Reveal Their Secret To Aging
"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."
#SciComm by @GrrlScientist
#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667
Pink Flamingos Reveal Their Secret To Aging
"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."
#SciComm by @GrrlScientist
#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667
Pink Flamingos Reveal Their Secret To Aging
"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."
#SciComm by @grrlscientist
#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667
Scientific Frontline
Eishi Noguchi
David Ojcius
DanStafford
Rhyothemis
GrrlScientist ⧖ Ⓥ SciComm 🇺🇦
GrrlScientist ⧖ Ⓥ 
GrrlScientist ⧖ Ⓥ 🇺🇦
GrrlScientist ⧖ Ⓥ 🇺🇦