🧬 If structure determines function, how can we optimize DNA therapeutics without accurately predicting their 3D shape?

🔗 Predicting Single-Stranded DNA Oligonucleotides 3D Structures: An Open Issue. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0127

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #DNA #ComputationalBiology #Bioinformatics #MolecularBiology #Aptamers #DNANanotechnology #GenomeEngineering #NucleicAcids

Postdoc in the Kwok Lab, City University of Hong Kong
City University of Hong Kong

See the full job description on jobRxiv: https://jobrxiv.org/job/city-university-of-hong-kong-27778-postdoc-in-the-kwok-lab-city-university-of-hong-kong-8/

#aptamers #chemicalbiology #LifeScience #RNA #rnabiology #ScienceJobs #hiring #research
https://jobrxiv.org/job/city-university-of-hong-kong-27778-postdoc-in-the-kwok-lab-city-university-of-hong-kong-8/?fsp_sid=11977

6-Jun-2025
Ultra-selective #aptamers give viruses a taste of their own medicine
Inspired by the way #viruses attach to cells, EPFL scientists have developed a method for engineering ultra-selective aptamers. The synthetic molecules bind to targets like viral spike proteins, making them useful for #biomedical #diagnostics and treatments

loving the acronym: #MEDUSA (Multivalent Evolved #DNA-based SUpramolecular Assemblies)

https://www.eurekalert.org/news-releases/1086043 #science #nanoworld

Inspired by the way #viruses attach to cells, @EPFL scientists have developed a method for engineering ultra-selective #aptamers: synthetic molecules that bind to specific targets like viral spike proteins.

Specifically, the team has published the first technique for producing multimeric aptamers that target protein complexes with unprecedented precision and functionality, making them extremely promising for biomedical diagnostics and treatments!

Read our news: https://actu.epfl.ch/news/ultra-selective-aptamers-give-viruses-a-taste-of-t/

The Global Aptamers Market is driven by Increasing Investment in Research and Development

According to Coherent Market Insights, The global Aptamers Market is estimated to be valued at USD 8.60 Bn in 2025 and is expected to exhibit a CAGR of 18% over the forecast period of 2025 to 2032.

Aptamers Market- https://timessquarereporter.com/business/aptamers-market-are-revolutionizing-healthcare-owing-to-their-selective-binding-capabilities

#CoherentMarketInsights #AptamersMarket #Aptamers #AptamersMarketAnalysis #PeptideAptamers

SciTech Chronicles. . . . . . . . .Mar 4th, 2025

https://bit.ly/stc030425

#Częstochowa-Mirów #smelting #SEM #metabolites #fatty #acids #1-linoleoyl-GPE #H5N1 #aerosol #electrochemical #aptamers #polyps #colibactin #epithelial #Nissle #Salto #cryovolcanoes

"RNA-Puzzles Round V dives into blind predictions by 18 modeling groups for 23 #RNA structures. 🧬

From #aptamers to #riboswitches, it highlights progress and challenges in RNA #3D #modeling.

Proud to contribute to this incredible journey! A heartfelt thank you to the organizers, collaborators, and the amazing community advancing RNA #structural #biology.

Together, we’re pushing the boundaries of #RNA3D, #StructuralBiology, #Bioinformatics, and #ComputationalBiology.

https://doi.org/10.1038/s41592-024-02543-9