Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis.

#RNASecondaryStructure #MutationalProfiling #5UTR #Riboswitches #RNAThermometers

https://www.nature.com/articles/s41587-025-02739-0

"RNA-Puzzles Round V dives into blind predictions by 18 modeling groups for 23 #RNA structures. 🧬

From #aptamers to #riboswitches, it highlights progress and challenges in RNA #3D #modeling.

Proud to contribute to this incredible journey! A heartfelt thank you to the organizers, collaborators, and the amazing community advancing RNA #structural #biology.

Together, we’re pushing the boundaries of #RNA3D, #StructuralBiology, #Bioinformatics, and #ComputationalBiology.

https://doi.org/10.1038/s41592-024-02543-9

Whoa, the supra-genetic regulatory mechanisms of biology continue to astound me!

They are also some incredibly pretty structures

https://en.wikipedia.org/wiki/Riboswitch

#StructuralBiology #Riboswitches #RNA