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Congratulations to Claudia Höbartner on being awarded the prestigious Albrecht-Kossel-Preis of the @gdch at #Biochemistry2026. A very well deserved honor.
Claudia gave an amazing award lecture on "Enzymes made of DNA and RNA".
#Biochemistry #Chemistry #ChemBio #RNA #DNA
CC: @GDCh_BioChem
RE: https://mstdn.science/@GDCh_BioChem/116245580449060063
Congratulations, Claudia!
Congratulations to Claudia Höbartner on being awarded the very prestigious Albrecht-Kossel-Preis by the @gdch at #Biochemistry2026!
Prof. Höbartner receives this award for the first structure of a DNAzyme and for the development of ribozymes with methyl transferase activity.
The award was presented by GDCh president, Ruth Bieringer, with a laudatio by Andrea Rentmeister.
We are excited that we could today award four Young Scientist Awards for outstanding publications and dissertations over the last two years.
The awardees are Johannes Morstein, Sarah Emmert, Frederik Schmidt and Lukas Zeisel. Congratulations to all awardees! (1/3)
The awardees are:
Johannes Morstein, "Overcoming the undruggable nature of GTPases" https://www.cell.com/cell/fulltext/S0092-8674(24)00908-5
Sarah Emmert, "TRaQ-G - A locally activatable glutathione sensor" https://www.nature.com/articles/s41557-023-01249-3
...
(2/3)
...
Frederik Schmidt, "The iron nitrogenase – a CO2 reductase? – Making feedstock chemicals from thin air" https://www.nature.com/articles/s41594-023-01124-2
Lukas Zeisel, "Rational design of 1,2-dichalcogenides unlocks selective probes for the thioredoxin system" https://pubs.acs.org/doi/abs/10.1021/jacs.3c11153
(3/3)
Using cryo-EM, Schmidt, Schulz, et al. solve the structure of the iron nitrogenase complex, which shows a unique architecture of alternative nitrogenases and suggests the G subunit to be involved in substrate channeling, stabilization of the cofactor and determining specificty among nitrogenase components.
Understanding the thioredoxin system is key to understanding cellular RedOx homeostasis.
Congratulations to Lukas Zeisel on being awarded one of the @GDCh_BioChem Young Scientist Awards for his work in the group of Oliver Thorn-Seshold in this field.
https://pubs.acs.org/doi/abs/10.1021/jacs.3c11153
#Biochemistry #Chemistry #ChemBio #Sensor #Fluorescence
Can CO2 be fixed into useful feedstock chemicals by enzymes?
Congratulations to Frederik Schmidt on being award one of the @GDCh_BioChem Young Scientist Awards for his work on the biochemical and structural characterization of an iron nitrogenase with potential for this application.
https://www.nature.com/articles/s41594-023-01124-2
#Biochemistry #Chemistry #StructuralBiology #CO2Fixation
GTPases have long been considered key examples of undruggable proteins. While this has been overcome for K-Ras using #CovalentInhibitors, for many other family member #DrugDevelopment has not been shown.
Congratulations to Johannes Morstein on winning one of the @GDCh_BioChem Young Scientist Awards for his work addressing this challenge by identifying druggable, allosteric pockets in several GTPases.
https://www.cell.com/cell/fulltext/S0092-8674(24)00908-5
#Biochemistry #ChemBio #GTP #GTPases #Chemistry
CC: @gdch
How can the concentration of glutathione be monitored with subcellular precision?
Congratulations to Sarah Emmert on receiving one of the @GDCh_BioChem Young Scientist Awards for her work in the lab of Pablo Rivera-Fuentes on addressing this question with fluorescent sensors.
https://www.nature.com/articles/s41557-023-01249-3
#Biochemistry #Fluorescence #Sensors #Chemistry #ChemBio #Award
GDCh Division of Biochemistry