Very insightful review by the group of Alexander Deiters in @[email protected] They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. doi.org/10.1039/d5cb... #ChemSky #ChemBio #NucleicAcids #RNA #DNA

Covalent aptamers: agents with...
Very insightful review by the group of Alexander Deiters in RSC Chemical Biology. They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. https://doi.org/10.1039/d5cb00133a
#Chemistry #ChemBio #NucleicAcids #RNA #DNA

6-Jun-2025
Ultra-selective #aptamers give viruses a taste of their own medicine
Inspired by the way #viruses attach to cells, EPFL scientists have developed a method for engineering ultra-selective aptamers. The synthetic molecules bind to targets like viral spike proteins, making them useful for #biomedical #diagnostics and treatments

loving the acronym: #MEDUSA (Multivalent Evolved #DNA-based SUpramolecular Assemblies)

https://www.eurekalert.org/news-releases/1086043 #science #nanoworld

Inspired by the way #viruses attach to cells, @EPFL scientists have developed a method for engineering ultra-selective #aptamers: synthetic molecules that bind to specific targets like viral spike proteins.

Specifically, the team has published the first technique for producing multimeric aptamers that target protein complexes with unprecedented precision and functionality, making them extremely promising for biomedical diagnostics and treatments!

Read our news: https://actu.epfl.ch/news/ultra-selective-aptamers-give-viruses-a-taste-of-t/

Ultra-selective aptamers give viruses a taste of their own medicine

Inspired by the way viruses attach to cells, EPFL scientists have developed a method for engineering ultra-selective aptamers. These synthetic molecules bind to specific targets like viral spike proteins, making them useful for biomedical diagnostics and treatments.

The Global Aptamers Market is driven by Increasing Investment in Research and Development

According to Coherent Market Insights, The global Aptamers Market is estimated to be valued at USD 8.60 Bn in 2025 and is expected to exhibit a CAGR of 18% over the forecast period of 2025 to 2032.

Aptamers Market- https://timessquarereporter.com/business/aptamers-market-are-revolutionizing-healthcare-owing-to-their-selective-binding-capabilities

#CoherentMarketInsights #AptamersMarket #Aptamers #AptamersMarketAnalysis #PeptideAptamers

Aptamers Market are Revolutionizing Healthcare Owing to their Selective Binding Capabilities | Times Square Reporter

The global Aptamers Market is estimated to be valued at USD 8.60 Bn in 2025 and is expected to exhibit a CAGR of 18% over the forecast period of 2025...

TimesSquareReporter
SciTech Chronicles. . . . . . . . .Mar 4th, 2025

With the eyes of a child you must come out see.... Vol II No 57 361 links Curated 2,700-Year-Old Meteorite Jewelry Unearthed in Poland. http...

"RNA-Puzzles Round V dives into blind predictions by 18 modeling groups for 23 #RNA structures. 🧬

From #aptamers to #riboswitches, it highlights progress and challenges in RNA #3D #modeling.

Proud to contribute to this incredible journey! A heartfelt thank you to the organizers, collaborators, and the amazing community advancing RNA #structural #biology.

Together, we’re pushing the boundaries of #RNA3D, #StructuralBiology, #Bioinformatics, and #ComputationalBiology.

https://doi.org/10.1038/s41592-024-02543-9

Meet Richard Napier, a JXB handling #editor who oversees manuscripts covering various topics such as #auxin, #protein structure, #signalling, receptors, #biosensors, #aptamers, #cytokinins, and chemical #biology 🌱
Researchers from North Carolina State University have developed a new generation of high-performance #DNA #aptamers and highly accurate drug sensors for #cocaine and other #opioids.
#Chemistry #Genetics #Pharmaceutical #sflorg
https://www.sflorg.com/2024/03/chm03042401.html
DNA Aptamer Drug Sensors Can Instantly Detect Cocaine, Heroin and Fentanyl – Even When Combined with Other Drugs

An aptamer is a short single strand of DNA or RNA that will bind to a specific molecule with high affinity

23-Jun-2023
Bridging the gap for precision medicine: nanofluidic aptamer nanoarray measures individual proteins

A pioneering step towards digital assays at cellular concentrations

https://www.eurekalert.org/news-releases/993362 #science #nanoworld #aptamers #proteins #nanofluidics #sensors

Bridging the gap for precision medicine: nanofluidic aptamer nanoarray measures individual proteins

An international team led by Professor Yan Xu from Osaka Metropolitan University has developed a groundbreaking nanofluidic device, named NANa, capable of stochastically capturing and digitally detecting individual proteins at cellular concentrations. This tool, vital for precision medicine, is designed to handle tiny volumes equivalent to a single cell's contents and can identify single biomolecules even in high-concentration environments. The team plans to conduct further demonstrations using actual cell samples and explore the integration of this tool with AI and biological big data. This research could potentially revolutionize personalized disease prevention and treatment.

EurekAlert!