πŸ’Š Can understanding receptor bias help us design safer, more selective GPCR drugs?

πŸ”— Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.039

πŸ“š CSBJ: https://www.csbj.org/

#GPCR #StructuralBiology #MolecularDynamics #NMR #Pharmacology #ProteinStructure #DrugDiscovery #ComputationalBiology #CellSignaling

PhD Student and Postdoc Positions in Tissue Patterning and Regeneration

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
PhD Student and Postdoc Positions in Tissue Patterning and Regeneration

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
PhD Student and Postdoc Positions in Tissue Patterning and Regeneration

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
PhD Student and Postdoc Positions in Tissue Patterning and Regeneration

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv

πŸ“£πŸ“£πŸ“£ Latest news from the NephroLab Cologne – more specifically, from our πŸ¦› Hippo- Team:
Our snRNA-Seq study on YAP and TAZ in kidney podocytes is now online open access in JASN! πŸ₯³ πŸŽ‰ πŸ™
Huge thanks to everyone on the team and the incredibly thorough reviewers at JASN!

Link: https://journals.lww.com/jasn/abstract/9900/transcriptional_regulators_yap_and_taz_have.598.aspx

#HippoSignaling #YAP #TAZ #Kidney #Kidneydisease #Science #snRNASeq #cellsignaling #FSGS #podocyte #Nephrology #Niere #Nephrolab #Nephrologie

@ukkoeln @UniKoeln @CECAD

The Basics of Purines and Pyrimidines: Understanding the Building Blocks of DNA and RNA

#Adenine, #CellSignaling, #Cytosine, #DNA, #EnzymeRegulation, #Guanine, #Purines, #Pyrimidines, #RNA, #Thymine, #Uracil #Genetics In the realm of molecular biology, few molecules are as crucial as purines and pyrimidines. These organic compounds serve as…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/15/the-basics-of-purines-and-pyrimidines-understanding-the-building-blocks-of-dna-and-rna/

The Basics of Purines and Pyrimidines: Understanding the Building Blocks of DNA and RNA

#Adenine, #CellSignaling, #Cytosine, #DNA, #EnzymeRegulation, #Guanine, #Purines, #Pyrimidines, #RNA, #Thymine, #Uracil #Genetics In the realm of molecular biology, few molecules are as crucial as …

Medical Microbiology & RDT Labs

Unveiling the Architect of Life: Exploring the Plasma Membrane

#CellAdhesion, #CellMembrane, #CellSignaling, #Communication, #Disease, #Homeostasis, #LipidByLayer, #Pathology, #PlasmaMembrane, #SelectivePermeability, #SemiPermeableMembrane, #UnitMembrane #CellBiology Composed primarily of lipids, proteins, and carbohydrates, the plasma membrane exhibits a dynamic and heterogeneous structure. Phospholipids, with their hydrophilic heads and hydrophobic tails, form the…

https://micrordt.wordpress.com/2024/04/25/unveiling-the-architect-of-life-exploring-the-plasma-membrane/

Unveiling the Architect of Life: Exploring the Plasma Membrane

#CellAdhesion, #CellMembrane, #CellSignaling, #Communication, #Disease, #Homeostasis, #LipidByLayer, #Pathology, #PlasmaMembrane, #SelectivePermeability, #SemiPermeableMembrane, #UnitMembrane #Cell…

Medical Microbiology & RDT Labs
@gpollara Is there a comprehensive resource that investigates the interferon signalling "landscape", also in conjunction with other microenvironmental pathways like cGAS or STING etc.? #cytokines #networks #CellSignaling #immunology #infection #immunotherapy

A developer of treatments for Alzheimer's disease that seeks to improve the condition of the brain's support cells is raising Β£48 million ($US 61 million) in its first venture round.

https://sciencebusiness.technewslit.com/?p=45307

#News #Press #Science #Business #Biotechnology #Neuroscience #AlzheimersDisease #Dementia #Astrocytes #Neurodegenerative #CellSignaling #Licensing #Finance #VentureCapital

Neuro Disease Biotech Gains $61M in Early Funds

A developer of treatments for Alzheimer's disease that seeks to improve the condition of the brain's support cells is raising Β£48 million ($US 61 million) in its first venture round.

Science and Enterprise