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I wonder if medications targeting the CGRP affective pain pathway could help ease fear, avoidance, and hypervigilance in neurodevelopmental disorders like autism.

Read here: https://www.sciencedaily.com/releases/2025/07/250710113151.htm

#NeurodevelopmentalDisorders
#Autism
#PTSD

How a hidden brain circuit fuels fibromyalgia, migraines, and PTSD

What if your brain is the reason some pain feels unbearable? Scientists at the Salk Institute have discovered a hidden brain circuit that gives pain its emotional punch—essentially transforming ordinary discomfort into lasting misery. This breakthrough sheds light on why some people suffer more intensely than others from conditions like fibromyalgia, migraines, and PTSD. By identifying the exact group of neurons that link physical pain to emotional suffering, the researchers may have found a new target for treating chronic pain—without relying on addictive medications.

ScienceDaily
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