Title: P2: Homeostasis of bio-systems as the first step of evolution. [2025-10-13 Mon]
decision making. #homeostasis #systems #evolution #feedback #feedforward
Title: P2: Homeostasis of bio-systems as the first step of evolution. [2025-10-13 Mon]
decision making. #homeostasis #systems #evolution #feedback #feedforward
Title: P1: Homeostasis of bio-systems as the first step of evolution. [2025-10-13 Mon]
a primitive decision-making "brain."
Are you more intrigued when something behaves lifelike?
As we explore consciousness origins, deeper questions
arise: How should conscious beings be valued?
Living organisms — just like any system — need:
1) resources
2) plan and stucture preserving mechanics
3) cells movement or some freedom for distributed #homeostasis #systems #evolution #feedback #feedforward
Title: P0: Homeostasis of bio-systems as the first step of evolution. [2025-10-13 Mon]
The image shows stem cell growth.
Symmetric division yields one cell type, while asymmetric
division creates two, supporting homeostasis through
alternating modes.
Negative feedback preserves structure. "no" restores
balance, while "yes" drives expansion.
Both feedback types underpin system evolution, acting as #homeostasis #systems #evolution #feedback #feedforward
El motor iónico de la supervivencia humana
La presencia indispensable del cloruro de sodio en la homeostasis celular
La sal común, o cloruro de sodio, no es un simple aditivo culinario, sino un compuesto químico fundamental cuya presencia determina la viabilidad de la vida humana. Desde una perspectiva evolutiva, los fluidos que bañan nuestras células replican la salinidad de los océanos primitivos donde se originaron los primeros organismos. Esta concentración salina es estrictamente necesaria para mantener el equilibrio osmótico, el cual regula la cantidad de agua dentro y fuera de las membranas celulares, evitando que las células colapsen o se destruyan por exceso de presión de forma irreversible.
A nivel neurológico y muscular, los iones de sodio y cloruro actúan como los conductores de la corriente eléctrica del cuerpo. La transmisión de los impulsos nerviosos desde el cerebro hacia el resto de los órganos depende enteramente de la bomba de sodio-potasio, un mecanismo biológico que genera gradientes de carga eléctrica a través de las membranas de las neuronas. Sin la cantidad exacta de sodio en el torrente sanguíneo, el corazón perdería la capacidad mecánica de contraerse y los músculos sufrirían parálisis debido a la ausencia de estímulo eléctrico medible.
El sistema renal trabaja de forma ininterrumpida para filtrar y mantener los niveles de este mineral en un rango homeostático preciso. Una alteración crítica por déficit, conocida médicamente como hiponatremia, provoca edema cerebral, confusión y fallos sistémicos letales, mientras que el exceso satura la capacidad de filtración y eleva la presión arterial de manera peligrosa. El cuerpo humano no puede sintetizar el sodio por sí mismo, lo que convierte la ingesta controlada de este mineral en un requerimiento biológico absoluto e incuestionable para la continuidad de las funciones vitales.
— Aetherius Eldritch, Periodista, Locutor, podcaster y bloger del fediverso.
I wrote a follow-up text to my previous thinking about AI, digital civilization, and what may come after the current hype cycle.
It is a attempt to frame AI not as a new industrial revolution, but as the final acceleration of the digital one and maybe the beginning of something more homeostatic.
https://medium.com/@igisho/the-last-industrial-revolution-28189b0df5d7
#AI #Technology #Philosophy #DigitalCivilization #IndustrialRevolution #Homeostasis
Short-term #synaptic #plasticity (#STP) transiently modulates synaptic strength based on recent activity. #ShortTermDepression #STD reduces efficacy during repeated activity, while #ShortTermFacilitation #STF can enhance responses to closely spaced #spikes. These dynamics shape #NeuralProcessing, #filtering, and synaptic #homeostasis. Here's a short #Python implementation and simulation in #NESTSimulator:
🌍 https://www.fabriziomusacchio.com/blog/2026-05-25-std_and_stf/
#CompNeuro #Neuroscience #NeuralDynamics #TsodyksMarkramModel
🧠🎨 New paper by Meyer et al: #astrocytic #sodium #homeostasis is not uniform. Using multiphoton #FLIM in #mouse #brain slices and #invivo, they show strong #cellular and #subcellular heterogeneity in astrocytic Na⁺ levels.
Processes contain more Na⁺ than somata, Na⁺ varies between #astrocyte branches, and distinct Na⁺/K⁺-ATPase subunit patterns help tune local K⁺ uptake and #glutamate-linked Na⁺ influx.
Master Index
A guided map across physics, biology, engineering, and AI—built around a simple idea
Persistence is not generated, but permitted.
Systems don’t fail because they “break.”
They fail because their boundaries were misclassified.
Core structure
state → constraint → resolution → persistence
From: - Titanic / Vasa / Challenger
– biological regulation
– AI hallucination & drift
– institutional collapse
Same pattern
only admissible states persist
This is the interface.
Start anywhere. Follow the path that fits.
#HybridMind42 #BoundaryDynamics #BoundaryArchitecture #BFPF #HQP
#Admissibility #ConstraintResolution #StateTransition #Persistence
#ComplexSystems #SystemsThinking #StructuralAnalysis #FailureAnalysis
#Physics #QuantumMechanics #Relativity #Lindblad #CPTP #Decoherence
#Biology #Physiology #Adaptation #Homeostasis
#ArtificialIntelligence #AI #LLM #AIAlignment #AIGovernance
#InstitutionalFailure #DecisionMaking
#Emergence #ScientificClarity
https://substack.com/@hybridmind42/note/c-252017333?r=75c2ac

What if systems don’t fail because they’re weak… but because their boundaries are wrong? I’ve just published the Master Index for the HybridMind42 series. It’s a guided map across everything explored so far: – why systems persist (or don’t) – how failure actually occurs – and why “selection” isn’t a process, but a result of constraint At the core is a simple shift: Persistence is not generated. It is permitted. From physics and biology to engineering and AI, the same structure keeps appearing: state → constraint → resolution → persistence This post isn’t a paper—it’s the front door. If you’re new, there’s a path in. If you’ve been following, this is the map. 🌿🏛️
`Notably, sleep deprivation, ultraviolet radiation, and mutagens increased neuronal DNA damage and sleep pressure, while spontaneous and induced sleep facilitated genome stability in both the diurnal and crepuscular cnidarians. These results suggest that DNA damage and cellular stress in simple nerve nets may have driven the evolution of sleep.`
https://doi.org/10.1038/s41467-025-67400-5
#cnidaria #invertebrates #marineBiology #neurology #neuroscience #evolution #sleep #homeostasis