Highly recommended household items for my fellow #ChronicIllness baddies:
1) A bed desk / Reading pillow / Bed Wedge (take your pick)
2) A weighted blanket
3) A bedside/portable basket for your essentials
4) A 1L insulated water bottle
5) Dimmable lights (IKEA’s system is quite affordable)
6) Honourable mentions: fidget toys, plushies, blankets, and other cozy items.
^^ (cont from first post)
If you’re wondering how you can help, there are a few answers to that question:
1) Find the people in your life living with disabilities, visible and/or invisible and ask them how you can meaningfully support them. Do it if you’re able.
2) For me, my main source of income is now my online shop at BrittBuilds3D. If you feel so inclined, supporting my shop can directly help me. https://brittbuilds3d.etsy.com - You can also place direct orders via DMs.
3) Most importantly: read about us, learn about us, and keep disabled people in your life even if you don’t understand what we are going through. Please don’t fade away.
🫶🏻
#medical #ph #disability #disabled #mecfs #pots #autoimmunity #LongCovid #Accessibility
That moment when you have to admit defeat and medically withdrawal from University due to the compounding effect of multiple disabilities/illnesses. 😞
I tried, friends. 
For two years, I gave it my all. 
Now, I’ve got at least 3-6 months off to focus on trying to stabilize my health. I’d like to return for spring/summer, but it’ll likely be in the fall.
(cont. on second post)
#medical #ph #disability #disabled #mecfs #pots #autoimmunity #LongCovid #Accessibility
'we did not attempt to identify the HuFl microbial mimic, as identifying it would lack translational relevance.'
then demonstrating that #Akkermansia contributes to #autoimmunity also offers little translational value. What exactly would you do?
https://www.biorxiv.org/content/10.64898/2025.12.04.691931v1
Pretty remarkable finding. The only question is, why isn’t everyone bald, given how common stress is?
Duchenne muscular dystrophy might have an autoimmune side after all. In mice, CD4⁺ T cells cause heart damage and removing them keeps the heart healthy. Big implications for future DMD treatments.
Duchenne muscular dystrophy (DMD) is a X-linked genetic disorder, in which cardiomyopathy represents a major cause of mortality. Although myocardial inflammation and fibrosis are hallmarks of the disease, the role of adaptive immunity in cardiac pathology remains poorly defined. Using the Mdx mouse model, we demonstrate that T and B lymphocytes accumulate in the heart and that activation occurs in heart-draining lymph nodes at an early disease stage. Mdx mice lacking adaptive immunity (Mdx-Scid) were protected from myocardial fibrosis and hypertrophic remodeling. Single-cell RNA sequencing revealed expansion of an inflammatory, matrisome-associated macrophage subset in Mdx but not Mdx-Scid hearts. Genetic deficiency or depletion of CD4⁺ T cells reduced left ventricular fibrosis and preserved systolic function. Moreover, adoptive transfer of T cells von Mdx mice induced myocardial fibrosis and dysfunction in healthy recipients. Our results identify autoreactive CD4⁺ T cells as key drivers of DMD-associated cardiomyopathy and suggest targeted modulation of adaptive immune responses as a potential therapeutic approach in DMD. ### Competing Interest Statement The authors have declared no competing interest. Deutsche Forschungsgemeinschaft, 453989101, 449933847 German Heart Research Foundation, https://ror.org/02yjb3a91, F/02/16
Research Assistant in Systems Immunology & Cell Design
University of Pennsylvania
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-pennsylvania-27778-research-assistant-in-systems-immunology-cell-design/
#Autoimmunity #bioengineering #cancerimmunology #molecularbiology #ScienceJobs #hiring #research
https://jobrxiv.org/job/university-of-pennsylvania-27778-research-assistant-in-systems-immunology-cell-design/?fsp_sid=3693
Discovery of C9orf72 as a Target of Autoimmune T Cell Responses in ALS
A new study published in *Nature* identifies C9orf72 as the first confirmed target of autoimmune T cell responses in amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by progressive motor neuron loss and a mean survival of around four years after diagnosis. ALS is associ... [More info]
Research Assistant in Systems Immunology & Cell Design
University of Pennsylvania
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-pennsylvania-27778-research-assistant-in-systems-immunology-cell-design/
#Autoimmunity #bioengineering #cancerimmunology #molecularbiology #ScienceJobs #hiring #research
https://jobrxiv.org/job/university-of-pennsylvania-27778-research-assistant-in-systems-immunology-cell-design/?fsp_sid=3287
Badass Britt 
David Usharauli
Sparwasser Lab
jobRxiv
qukahnata at KillBait