#SingleCell #Omics v2.11.8 bit.ly/scellmarket @albertvilella

Google Docs
scRepli-RamDA-seq: a multi-omics technology enabling the analysis of gene expression dynamics during S-phase - Nature Communications

The authors present scRR-seq, a single-cell multi-omics tool that directly links DNA changes to gene expression and enables simultaneous analysis of DNA replication, DNA copy number variation, and transcription.

Nature
#SingleCell #Omics v2.11.8 bit.ly/scellmarket @albertvilella

Google Docs
Mapping single-cell diploid chromatin fiber architectures using DAF-seq - Nature Biotechnology

Single-molecule chromatin fiber sequencing exposes single-cell-level heterogeneity in the chromatin architecture of individual regulatory elements.

Nature
We are excited to announce a new training course on Bgee 🧬
Course: Gene Expression made Useful Easily: Tools and Database of Bgee
Date: Friday 29 May 2026
Taught by: the Bgee team (Frédéric Bastian and Marc Robinson-Rechavi)
Learn more: https://www.sib.swiss/training/course/20260529_BGEEL
#bioinformatics #training #RNAseq #singlecell #GeneExpression #bgee
@SIB @marcrr @fbastian
Gene Expression made Useful Easily: Tools and Database of Bgee

Attendance is free of charge; however, registration is mandatory. Overview Bgee is a curated database of gene expression in animals, including model s

Pipeline release! nf-core/pixelator v2.3.0 - nf-core/pixelator 2.3.0!
Pipeline to generate Molecular Pixelation data with Pixelator (Pixelgen Technologies AB)
Please see the changelog: https://github.com/nf-core/pixelator/releases/tag/2.3.0

#molecularpixelation #pixelator #pixelgentechnologies #proteins #singlecell #singlecellomics #nfcore #openscience #nextflow #bioinformatics

Release nf-core/pixelator 2.3.0 · nf-core/pixelator

[2.3.0] - 2025-12-11 From this release onwards, there will not be a default panel selected, i.e. as a user you must specify an exact version of the panel you want to use in your samplesheet, e.g. p...

GitHub

#Special
#RNA-Sequenzierung im Fokus: Von Parasiten über Darmbakterien bis zum Gehirn - Mario Rembold zeigt im Artikel, wie entscheidend die Probenvorbereitung für aussagekräftige RNA-Seq-Daten ist – und das von Einzelzell- und räumlicher Transkriptomik bis zur Long-Read-Sequenzierung langer neuronaler Transkripte:

https://www.laborjournal.de/rubric/methoden/methoden/v316.php

#laborjournal #lifesciences #RNASeq #SingleCell #LongRead #Transkriptomik

@jlugiessen

🧬 Breakthrough in single-cell RNA-seq! PB10X method revolutionizes TCR profiling, detecting 80% paired chains with unprecedented flexibility. 🔬 Game-changer for immunology research! #Genomics #SingleCell #Immunology https://emmecola.github.io/genomics-daily
Genomics Daily

My GitHub page

Moreno Colaiacovo
6/ Lastly, in https://www.nature.com/articles/s41592-023-02003-w. the observed sensitivity deficits stem from three sources: (1) poor annotation of 3′ gene ends; (2) issues with intronic read incorporation; and (3) gene overlap-derived read loss. #singlecell #RNAseq
Recovery of missing single-cell RNA-sequencing data with optimized transcriptomic references - Nature Methods

This paper presents an improved approach for mapping single-cell RNA-seq reads with optimized transcriptomic references, which markedly recovers previously missing gene expression data.

Nature

Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes

https://www.nature.com/articles/s41564-025-02167-5

#viruses #SingleCell #marine #ocean

Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes - Nature Microbiology

Environmental micro-compartment genomics provides efficient and high-throughput single-particle DNA sequencing that captures overlooked members of microbial communities.

Nature